Recruiting

NCT Number: NCT06676137

An Observational Study of Coronary Microvascular Disease of China

Non-obstructive coronary heart disease refers to patients with angina pectoris without significant narrowing of the epicardial vessels. Coronary microvascular disease(CMD) is a kind of non-obstructive coronary heart disease, and its clinical detection rate is increasing, seriously affecting the quality of life of patients, and increasing the risk of cardiovascular adverse events, but its mechanism has not been fully understood. This study will prospectively collect patients who meet the diagnosis of CMD, observe the development and outcome of the disease, and explore its occurrence and development mechanism.

Recruiting

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Key information

Conditions

Coronary Microvascular Disease Angina Pectoris Cardiovascular Diseases Heart Diseases Microvascular Angina Myocardial Ischemia Vascular Diseases

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Fuwai central China cardiovascular hospotial

Zhengzhou, 450003, China

Location status: Recruiting

Location contact

Qingbo Shi

PRINCIPAL_INVESTIGATOR

Quan Guo

CONTACT

[email protected]

+8615670510031

Yang Gao

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Angina symptoms
Objective evidence of myocardial ischemia
Coronary angiography was normal,irregular tube wall, or stenosis <50%

Exclusion criteria

People under the age of 18
Non-cardiogenic chest pain and other heart conditions such as variant angina, cardiomyopathy, myocarditis or valvular heart disease

Treatment and study plan

Primary outcomes

Establish a Registry of CMD patients in China

Time frame: 5 years

Study contacts

Contact information is provided by the study sponsor or research team.

Quan Guo

CONTACT

[email protected]

+8615670510031

Sponsors and collaborators

Lead sponsor

Henan Institute of Cardiovascular Epidemiology

Other

Registry information

Official study title

China Coronary Microvascular Disease(CCMD) Registry

Acronym: CCMD

Important dates

Study start: 2024
Primary completion: 2028
Study completion: 2029
First posted: Nov 6, 2024
Registry last updated: Aug 20, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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