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NCT Number: NCT06661499

An Observational Clinical Study on the Construction of an Artificial Neural Network Model for ICU Pneumonia

To achieve rapid, intelligent and accurate microbiological diagnosis and treatment for ICU pneumonia, an artificial neural network model for microbiological diagnosis is established, which depends on many clinical cases and machine deep learning from clinical experts' judgements according to species-specific rapid detection of pathogenic bacteria and other clinical parameter variables of patients.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

This study is a prospective single-centre observational study, 600 ICU pneumonia patients are expected to be selected as the observation object, and the lower respiratory secretions of patients on d1, d3 and d7 after enrollment are collected for species-specific rapid detection and microbial culture, while the general information of the patients and the clinical information of the corresponding time points on d1, d3 and d7 are collected. Two experienced senior physicians were organized to determine whether the microbial results were colonized or infected, and an artificial neural network model for rapid and intelligent diagnosis of pathogenic microorganisms in ICU pneumonia will be established and validated through multi-dimensional machine learning.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • aged ≥18 years;
  • agreed to obtain lower respiratory specimens for rapid testing of pathogenic bacteria;
  • all were enrolled by an experienced physician who dynamically determined that the microorganisms were in a colonised or infected state;
  • signed an informed consent form.

Exclusion criteria

  • pregnant women;
  • lactating women;
  • patients who could not obtain lower respiratory specimens;

Treatment and study plan

establish an artificial neural network model

Other

to establish an artificial neural network model for pathogen diagnosis in ICU pneumonia

Primary outcomes

  1. clinical evaluation of each microbial detected whether in colonization or infection

    Time frame: day1,day3 and day7 after enrollment

    Two experienced senior physicians are organized to determine whether the microbial are colonized or infected according to clinical values.

Study contacts

Contact information is provided by the study sponsor or research team.

Yan Wang, Master

CONTACT

[email protected]

+86 18905150275

Sponsors and collaborators

Lead sponsor

Chinese Medical Association

Network

Registry information

Official study title

An Observational Clinical Study on the Construction of an Artificial Neural Network Model for Rapid Intelligent Diagnosis of Microorganisms in ICU Pneumonia Based on Species-specific Rapid Detection of Pathogenic Bacteria

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Oct 28, 2024
Registry last updated
Oct 28, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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