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NCT Number: NCT07666360

An Investigation of Cranio-Cervico-Mandibular Factors Predicting the Severity of Temporomandibular Disorders

This cross-sectional study will examine the relationship between mandibular dysfunction, cervical joint position sense, craniovertebral angle, neck pain, and temporomandibular dysfunction (TMD) severity. TMD severity, mandibular function, cervical proprioception, craniovertebral angle, and neck pain history will be assessed using standardized clinical tools and questionnaires. The study will evaluate the associations between these variables and determine the factors that may predict TMD severity.

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Key information

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Ankara Yıldırım Beyazıt University, Department of Physiotherapy and Rehabilitation

Ankara, Turkey (Türkiye)

Location status: Recruiting

Location contact

Sevilay Seda BAŞ

CONTACT

[email protected]

+9 0 (312) 906 1683

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Fonseca Anamnestic Index score > 15
  • aged 18 years and older

Exclusion criteria

  • Received medical, orthodontic, or physiotherapy treatment targeting the temporomandibular joint and/or cervical region within the past six months
  • used analgesic, anti-inflammatory, or muscle relaxant medications
  • history of cervical spine or cranio-cervical surgery or major trauma
  • a history of facial or TMJ trauma, TMJ subluxation or dislocation
  • partial or complete dental prostheses
  • had missing teeth
  • neurological, rheumatological, or systemic inflammatory diseases

Treatment and study plan

Assessments

Other

No intervention was applied.

Primary outcomes

  1. Temporomandibular Dysfunction Severity

    Time frame: Single assessment at baseline (cross-sectional evaluation)

    TMD severity will be assessed using the Fonseca Anamnestic Index, which evaluates the severity of temporomandibular dysfunction symptoms. It is a 10-item self-report questionnaire. Each item is scored as "Yes" (10 points), "Sometimes" (5 points), or "No" (0 points), with a total score calculated by summing all items.

Secondary outcomes

  1. Cervical Extension Joint Position Sense

    Time frame: Single assessment at baseline (cross-sectional evaluation)

    Cervical extension joint position sense will be assessed in a sitting position using an Acumar dual digital inclinometer. Participants will be asked to actively move their neck to 30° of cervical extension, memorize the target position, and then reproduce the same angle. The procedure will be repeated three times, and the average absolute error will be recorded.

  2. Cervical Flexion Joint Position Sense

    Time frame: Single assessment at baseline (cross-sectional evaluation)

    Cervical flexion joint position sense will be assessed in a sitting position using an Acumar dual digital inclinometer. Participants will be asked to actively move their neck to 30° of cervical flexion, memorize the target position, and then reproduce the same angle. The procedure will be repeated three times, and the average absolute error will be recorded.

  3. Cervical Lateral Flexion Joint Position Sense

    Time frame: Single assessment at baseline (cross-sectional evaluation)

    Cervical lateral flexion joint position sense will be assessed in a sitting position using an Acumar dual digital inclinometer. Participants will be asked to actively move their neck to 30° of lateral flexion, memorize the target position, and then reproduce the same angle. The procedure will be repeated three times, and the average absolute error will be recorded.

  4. Cervical Rotation Joint Position Sense

    Time frame: Single assessment at baseline (cross-sectional evaluation)

    Cervical rotation joint position sense will be assessed in a supine position using an Acumar dual digital inclinometer. Participants will be asked to actively rotate their head to 50° of cervical rotation, memorize the target position, and then reproduce the same angle. The procedure will be repeated three times, and the mean absolute error will be recorded.

  5. Craniovertebral Angle

    Time frame: Single assessment at baseline (cross-sectional evaluation)

    Craniovertebral angle will be measured using a two-dimensional image analysis method with Kinovea software from standardized lateral photographs. The tragus and C7 vertebra will be used as anatomical reference points to calculate the angle, and the mean of three measurements will be recorded for each participant.

  6. Neck Musculoskeletal Symptoms

    Time frame: Single assessment at baseline (cross-sectional evaluation)

    Musculoskeletal symptoms will be assessed using the Standardized Nordic Musculoskeletal Questionnaire. The questionnaire evaluates the presence of symptoms in different body regions over the past 12 months and past 7 days. Only neck pain-related variables will be used for analysis in line with the study objectives, while other data will be reported descriptively.

  7. Mandibular Function Impairment Questionnaire

    Time frame: Single assessment at baseline (cross-sectional evaluation)

    Mandibular function will be assessed using the Mandibular Function Impairment Questionnaire (MFIQ). The MFIQ is a 17-item self-report scale evaluating functional limitations during activities such as chewing, speaking, and yawning. Each item is scored on a 0-4 Likert scale, with higher scores indicating greater impairment.

Study contacts

Contact information is provided by the study sponsor or research team.

Sevilay Seda BAŞ, PhD

CONTACT

[email protected]

+90 (312) 906 1683

Sponsors and collaborators

Lead sponsor

sevilay seda bas

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jun 24, 2026
Registry last updated
Jun 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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