An Imaging Study of Polyvascular Disease

Inclusion criteria

Task 1:

• Patients with coronary artery disease (≥50% stenosis in any coronary artery on coronary angiography)
• Age ≥18 years old
• Proposed OCT-IVUS integrated imaging system
• able to provide written informed consent prior to the start of any procedures related to the study.

Task 2:

• patients with coronary artery disease (coronary angiography reveals ≥50% degree of stenosis in any coronary artery) and patients with stroke or TIA (confirmed by a neurologist)
• Age ≥ 18 years
• able to provide written informed consent prior to the start of any procedures related to the study.

Exclusion criteria

Task 1:

• severely tortuous/calcified coronary arteries with anticipated difficulty in completing the OCT-IVUS integrated imaging system
• uncontrolled congestive heart failure or acute left heart failure;plan
• claustrophobia;
• left main stem occlusion;
• proposed coronary artery bypass grafting (CABG);
• uncontrolled severe ventricular arrhythmia;
• active bleeding or severe bleeding tendency;
• acute stroke;
• patients with hemodynamic instability or unstable cardiac electrical activity (including shock) ;
• severe renal insufficiency and/or anuria, except in cases where dialysis treatment has been planned;
• contraindications to the application of contrast media;
• patients who are severely uncooperative due to psychiatric or serious systemic illness;
• Patients who, in the opinion of the investigator, are unsuitable for participation in the study.

Task 2:

• patients who are unable to comply with the follow-up schedule;
• uncontrolled congestive heart failure or acute left heart failure;
• patients with a life expectancy of less than 6 months;
• left main stem occlusion;
• proposed coronary artery bypass grafting (CABG);
• uncontrolled severe ventricular arrhythmia;
• active bleeding or severe bleeding tendency;
• patients with hemodynamic instability or unstable cardiac electrical activity (including shock) ;
• severe renal insufficiency and/or anuria, except in cases where dialysis treatment has been planned;
• contraindications to the application of contrast media;
• patients who are severely uncooperative due to psychiatric or serious systemic illness;
• patients who, in the opinion of the investigator, are not suitable for participation in the study.