An Evaluation of Tailored Messages to Address Parental Questions About HPV Vaccination

Attitudes will be assessed through a Web-based survey administered by Survey Sampling International (SSI). The projected sample size is approximately 3,500, comprising mothers or female guardians of at least one child aged 11-14 who live in the United States. The survey will take no more than 20 minutes to complete. Mothers who indicate that they do not plan to vaccinate their children in the next year will be randomized to view brief videos tailored to their questions or concerns about HPV vaccination. The outcome of interest is intention to vaccinate. Mothers who have vaccinated their child or intend to vaccinate their child will be asked a separate set of questions relevant to this information.

Mothers who indicate that they do not intend to vaccinate their child against HPV will be asked about their questions or concerns regarding HPV vaccination (from a pre-populated list of common concerns). Mothers will be randomized to one of three arms: 1. A general information video; 2. The general video plus a video addressing their top concern; or 3. The general video plus one or more videos addressing all of their concerns. Each video is less than 50 seconds in length.

Inclusion criteria

• 18 years of age or older
• Lives in one of 26 US states with lower rates of HPV vaccination (New Jersey, Virginia, West Virginia, Alabama, Florida, Kentucky, Mississippi, North Carolina, South Carolina, Tennessee, Indiana, Minnesota, Ohio, Arkansas, Louisiana, New Mexico, Oklahoma, Kansas, Missouri, Montana, South Dakota, Utah, Wyoming, Idaho, Texas, Iowa)
• Mother or female legal guardian of at least one child aged 11-14 years
• Able to read and understand English
• Target child must not have received any doses of HPV vaccine
• The mother/respondent must indicate that she is not sure that she will vaccinate the target child in the next year.

Exclusion criteria

• Under 18 years of age
• Not a mother or female legal guardian of at least one child ages 11-14 years
• Not living in the United States or in one of the above designated states within the U.S.
• Not able to understand or read English
• Target child has already received at least 1 dose of HPV vaccine
• The mother/respondent indicates (before the intervention) that she definitely intends to vaccinate the target child with HPV vaccine in the next year.