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Completed

NCT Number: NCT05981443

An Analysis of Dermabond vs. Non-Absorbable Sutures in Skin Closure for Brow Ptosis Procedures

The goal of this clinical trial is to compare Dermabond with non-absorbable sutures in skin closure after brow ptosis surgery. The main questions it aims to answer are:

* if Dermabond provides equivalent wound healing compared to conventional non-absorbable skin suture techniques * if Dermabond provides equivalent scar appearance compared to conventional non-absorbable suture techniques * if Dermabond results in equivalent complication rates compared to conventional non-absorbable suture techniques Participants will have be randomly selected to have either Dermabond or non-absorbable suture closure methods. Scar analysis and both participant and provider surveys will be performed to assess the differences between groups, if any.

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Key information

Conditions

Brow Ptosis Surgical Wound Wounds and Injuries

Age range

18 year–100 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Kentucky

Lexington, Kentucky, 40508, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients undergoing bilateral direct excision brow lift for brow ptosis at the University of Kentucky Medical Center.
  • Patients > 18 years of age.
  • Patients must be able to follow up at the specified intervals.
  • Patients who are able to give their own informed consent.
  • Health Status: Variable health status reflective of general population of Kentucky. Patients will be healthy enough to be seen in an office setting.
  • All patients will need to be proficient in the English language to understand the scale used for scar assessment

Exclusion criteria

  • Patients <18 years of age or >100
  • Allergy to Dermabond
  • Adults with impaired consent capacity
  • Incarcerated individuals

Treatment and study plan

Dermabond

Device

Use of Dermabond to close surgical incisions instead of non-absorbable sutures

Non-Absorbable Sutures

Other

Use of conventional non-absorbable sutures to close surgical incisions

Primary outcomes

  1. Scar Appearance

    Time frame: 10 days

    Patient and Observer Scar Assessment Scale filled out by both patient and provider at both postoperative visits of both Dermabond and non-absorbable sutures. This survey is scaled from 0-10, with 0 being normal skin and 10 being very different skin. Lower scores are desired on this survey.

  2. Scar Appearance

    Time frame: 6 weeks

    Patient and Observer Scar Assessment Scale filled out by both patient and provider at both postoperative visits of both Dermabond and non-absorbable sutures. This survey is scaled from 0-10, with 0 being normal skin and 10 being very different skin. Lower scores are desired on this survey.

  3. Number of Participants With Complications

    Time frame: 6 weeks

    Complications of both Dermabond and non-absorbable sutures to include dehiscence and infection

Sponsors and collaborators

Lead sponsor

Cody Blanchard

Other

Registry information

Official study title

Scar Analysis in Direct Excision Brow Lift: Comparing Octyl-2- Cyanoacrylate (Dermabond) Versus Non-absorbable Sutures

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Aug 8, 2023
Registry last updated
Apr 24, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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