An Acupuncture Study for Prostate Cancer Survivors With Urinary Issues

The purpose of this study is to test whether acupuncture can improve nocturia in prostate cancer survivors. This is the first time acupuncture is being studied for nocturia in prostate cancer survivors. Researchers will see if acupuncture is a practical treatment option for prostate cancer survivors with nocturia. The study will also look at the effect acupuncture has on nocturia and other symptoms prostate cancer survivors experience such as insomnia, hot flashes, anxiety, depression, tiredness (fatigue), sexual dysfunction, and cognitive (mental) difficulties.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Survivorship Genital Diseases Genital Diseases, Male Genital Neoplasms, Male Lower Urinary Tract Symptoms Male Urogenital Diseases Neoplasms Neoplasms by Site Nocturia Pathological Conditions, Signs and Symptoms Prostate Cancer Prostatic Diseases Prostatic Neoplasms Signs and Symptoms Urogenital Diseases Urogenital Neoplasms Urological Manifestations

Age range

18 year and older

Sex eligibility

Male

Study type

Interventional

Phase

Phase 1 / Phase 2

Primary location

Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age 18 or older
Prior PC diagnosis
No evidence of Prostate Cancer
Clinically meaningful nocturia, defined as ≥2 nocturia episodes every night for the past month

Exclusion criteria

<1 month since completion of PC treatment (surgery, chemotherapy, radiation, ADT)
Score of ≥5 on the STOP-Bang questionnaire indicative of high risk of moderate-to severe obstructive sleep apnea
Other untreated primary sleep disorder (e.g. delayed/advanced sleep phase syndrome)
Untreated primary psychiatric disorder (e.g. bipolar disorder, schizophrenia, substance abuse, dementia)
Initiation of new medications for urinary symptoms in the past 4 weeks
Altered dosing of medications for urinary symptoms in the past 4 weeks
Plan to initiate/change medications or other treatments (e.g. surgery, behavioral intervention, complementary therapies) for urinary symptoms during the study
Implanted electronically charged medical device
Unable to provide consent for himself
Unwilling to adhere to all study-related procedures

Treatment and study plan

Acupuncture

Procedure

10 treatments of acupuncture over the course of 10 weeks

Waitlist Control

Other

The waitlist control group will not receive any acupuncture treatments during the 14-week waiting period. Patients in waitlist control group will have the option to receive up to 10 acupuncture treatments after a 14-week waiting period.

questionnaires

Other

Patients will complete Patient Reported Outcomes (PRO)

Primary outcomes

success

Time frame: 1 year

If a participant completes at least 8 out of 10 acupuncture sessions. Feasibility will be evaluated based on the respective definitions of success for the acupuncture.

Sponsors and collaborators

Lead sponsor

Memorial Sloan Kettering Cancer Center

Other

Registry information

Official study title

Nocturia in Prostate Cancer Survivors - Acupuncture Pilot Study (NOCTURNAL)

Important dates

Study start: 2022
Primary completion: 2026
Study completion: 2026
First posted: Sep 14, 2022
Registry last updated: Oct 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Active, Not Recruiting