Skip to main content
OpenTrials
Completed

NCT Number: NCT02228759

Ambulatory Continuous Adductor Canal Block to Facilitate Same Day Discharge Following Total Knee Arthroplasty: A Pilot Study

Patients scheduled to undergo total knee arthroplasty will receive motor sparing knee blocks with continuous adductor canal block along with multimodal analgesia started pre-operatively and continued into the postoperative period. The study will evaluate the feasibility of home discharge within the first 24 hours following total knee arthroplasty. We will also evaluate the pain scores in the first 5 days following the surgery, causes of delayed discharge and any adverse events.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Knee Osteoarthritis Arthritis Joint Diseases Musculoskeletal Diseases Neurologic Manifestations Osteoarthritis Osteoarthritis, Knee Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Rheumatic Diseases Signs and Symptoms

Age range

40 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University hospital, London Health Sciences centre

London, Ontario, N6A 5A5, Canada

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male and females of 40-70years of age
  • Scheduled to undergo unilateral primary total knee arthroplasty
  • ASA Class I, II

Exclusion criteria

  • ASA 3, 4
  • Revision surgery
  • Narcotic dependent (opioid intake morphine equivalent > 10 mg/ day for more than 3 months)
  • Other sources of chronic pain like fibromyalgia
  • Patients with associated significant cardiac, CNS or respiratory disease (poor cardio-respiratory reserve)
  • Major conduction defects in EKG (bifascilular block, CHB); significant valvular heart disease
  • Recent MI/ Stroke/ CHF (in the past 3 months)
  • BMI> 35
  • Obstructive sleep apnea (AHI > 15)
  • Patients with coexisting hematological disorder or with deranged coagulation parameters.
  • Patients with pre-existing major organ dysfunction such as hepatic and renal failure.
  • Psychiatric illnesses
  • Uncontrolled diabetes mellitus
  • Lack of informed consent.
  • Allergy to any of the drugs used in the study
  • Preoperative neurological deficits
  • Use of walking aids preoperatively
  • Living alone (Lack of Chaperone/home help)
  • Language barrier
  • Contralateral leg weakness
  • Pregnancy

Treatment and study plan

Adductor canal block

Procedure

All patients will recieve fast tracking with reduced fasting times, multimodal analgesia and adductor canal block

Primary outcomes

  1. percentage of patients discharged at 23 hours based on a composite of various factors represented on a pre-determined criteria

    Time frame: 24 hours

Secondary outcomes

  1. first 24 hour pain scores

    Time frame: 24 hours

  2. first 96 hour pain scores

    Time frame: 96 hours

  3. Rescue analgesic frequency

    Time frame: 24 hours

  4. total analgesic usage in the first 24 and 96 postoperative hours

    Time frame: 96 hours

Sponsors and collaborators

Lead sponsor

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Other

Registry information

Important dates

Study start
2015
Primary completion
2015
Study completion
2015
First posted
Aug 29, 2014
Registry last updated
Mar 9, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.