Ambulation Study in Multiple Sclerosis

This study includes:

Three study visits to the MS Center at Evergreen; wearing a pedometer for two, one-week periods to record walking during regular daily activities; keeping a diary for any walking problems such as falls and slips.

Subjects must meet the following criteria:

Diagnosis of MS (any form); 18-70 years of age; be on stable MS treatment OR no MS treatment for the last three months; no scheduled hospitalization in the next six months.

Inclusion criteria

• Subject must have sufficient cognitive ability to maintain a falls diary and follow instructions for wearing the pedometer
• Subject must have clinically definite MS according to McDonald criteria
• Subject must have EDSS between 0-6.5
• Subject must be aged 18-70
• Subjects must be given informed consent
• Subjects must be stable on disease modifying therapy or no therapy for at least three months before entry into study

Exclusion criteria

• No MS relapse within the last 30 days
• Subjects must have no scheduled major hospitalizations or surgical procedures during the study time frame. Hospitalization during the study may result in removal from the study
• Medical conditions other than MS that might significantly impact ambulatory activity (such as angina pectoris) in the judgement of the investigators
• History or suspicion of non-compliance in the judgement of the investigators