Alternative Measurements of Cough Pressure and Effects of Epidural Anaesthesia on Cough Pressure

Pressure generated by cough is an expression of expiratory muscle strength. Cough pressure (Pcough) is usually measured with gastric and/or esophageal catheters, but these are often either inconvenient or uncomfortable for the patient. The aim of this study was to evaluate whether central venous, vesical or rectal catheters could be useful to measure cough pressures as alternative sites to standard esophageal and gastric balloons.

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Key information

Conditions

Respiratory Physiology

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hospital del Mar

Barcelona, 08003, Spain

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients aged 18 to 75 years and scheduled for colon cancer surgery were recruited.
Informed consent signed.

Exclusion criteria

Rectal surgery, advanced cancer, abdominal wall disorders, respiratory or neuromuscular illness, body mass index > 30, chronic pain, pregnancy and inability to cough adequately.

Treatment and study plan

Cough pressure measurement

Procedure

Pcough

Device

Primary outcomes

Cough pressure

Time frame: From baseline until 1 hour

Sponsors and collaborators

Lead sponsor

Parc de Salut Mar

Other

Registry information

Acronym: ESPIRATOS

Important dates

Study start: 2005
Primary completion: 2008
Study completion: 2009
First posted: Nov 7, 2016
Registry last updated: Nov 7, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed