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NCT Number: NCT07110116

Alternate Nostril Breathing With Incentive Spirometry on Lung Function Among Asthma Patients

To compare effects of Alternate Nostril Breathing exercise with incentive spirometer on lung functions (forced vital capacity, forced expiratory volume, and peak expiratory flow rate) in Asthma patients.

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Key information

Conditions

Asthma Bronchial Diseases Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Lung Diseases Lung Diseases, Obstructive Respiratory Hypersensitivity Respiratory Tract Diseases

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Allied Specialist Hospital & Clinics

Abbottābād, Khyber PkahtoonKhwa, 22020, Pakistan

Location status: Recruiting

Location contact

Hira Qazi, MSPT

CONTACT

[email protected]

+92 319 5523996

Hira Qazi, MSPT

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosed male & female asthma patients of age 18-60 years.
  • Patients with mild to moderate asthma having predicted FEV1 between 60-80%.
  • Stable asthma condition without recent exacerbations.
  • Able to perform spirometry and follow instructions for the interventions.
  • No recent respiratory infections.

Exclusion criteria

  • Patients with severe asthma (FEV1 < 60% predicted).
  • Patients having respiratory infections, recent exacerbations or other comorbidities.
  • Inability to perform breathing exercises or spirometry.
  • Patients using medications like oral steroids, beta blockers.
  • Pregnant women due to potential risks with breathing exercises.

Treatment and study plan

Alternate nostril breathing with Incentive Spirometery

Other

Participants in experimental group were instructed to close their left nostril by left index finger and inhale through their right nostril for six seconds, then closing the right nostril and holding breath for six seconds. Afterward, they exhaled through the left nostril slowly for six seconds. Next, they inhaled through left nostril, keeping the right nostril closed for six seconds then hold the breath by closing both nostrils for six seconds subsequently, and then exhaled through the right nostril, keeping the left closed for six seconds repeating these steps several times for 10 minutes

Incentive Spirometery

Other

The control group participants were asked to do breathing exercise with incentive spirometry. The subject is asked to create a tight seal around the mouthpiece and asked to inhale deeply and slowly and the subject would observe the flow meter for visual feedback of his/her effort. At the end of the inspiration the subject is asked to sustain the inhalation 2-3 seconds to facilitate the Inspiratory hold. Subject relaxes the seal around the mouthpiece and exhales. Normal breathing is taken, then the exhalation phase in the incentive spirometry is done and the whole cycle is repeated 5 - 10 times thrice a day over a period 6 weeks

Primary outcomes

  1. Forced expiratory volume in 1 second

    Time frame: 6 week

    Forced Expiratory Volume in 1 second (FEV1) is a measurement of how much air a person can forcefully exhale from their lungs in one second

  2. Forced Vital Capicity

    Time frame: 6 week

    Forced vital capacity (FVC) is a measurement of lung function that quantifies the maximum amount of air a person can forcefully exhale after taking the deepest breath possible

  3. Peak Expiratory Flow Rate

    Time frame: 6 week

    Peak expiratory flow rate (PEFR) measures the maximum speed of air that a person can forcefully exhale in one breath

  4. Asthama Control Test

    Time frame: 6 week

    The Asthma Control Test (ACT) is scored by assigning a value from 1 to 5 to each response in the 5-question survey, then summing these values for a total score ranging from 5 to 25. A higher score indicates better asthma control. A score of 20 or higher generally suggests well-controlled asthma.

  5. Asthama Quality of Life Questionaire with standardized Activities

    Time frame: 6 week

    The Standardized Asthma Quality of Life Questionnaire (AQLQ(S)) is a 32-item questionnaire used to assess the impact of asthma on an individual's quality of life, specifically focusing on the physical, emotional, and social aspects. 7-point Likert scale (7 = not impaired at all - 1 = severely impaired). Scores range 1-7, with higher scores indicating better quality of life.

Study contacts

Contact information is provided by the study sponsor or research team.

Muhammad Iqbal Tariq, PhD*

CONTACT

[email protected]

03338236752

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Comparison of Effects of Alternate Nostril Breathing Exercise With Incentive Spirometer Technique on Lung Functions Among Asthma Patients

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Aug 7, 2025
Registry last updated
Sep 5, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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