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Completed

NCT Number: NCT05304299

Alleviating Effects Against High Intraocular Pressure by Oral Intake of Cordyceps Cicadae Mycelia

This study will investigate the effects of lowering intraocular pressure by oral intake of Cordyceps cicadae mycelia, to provide evidence-based data for high intraocular pressure relief.

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Key information

Conditions

Age range

20 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Han-Hsin Chang

Taichung, Taiwan

About this study

Study purpose This study investigated the effeicacy of oral Cordyceps cicadae mycelia for the relief of high intraocular pressure.

Subjects

  • The total recruitment of subjects is 60 people, aged between 20 to 75 years.
  • Subjects with intraocular pressure more than or equal to 21 mmHg are included, irrespective of whether on us of Taflotan (saflutan).

Methods

  • Informed consents will be obtained from subjects first. The subjects with pre-test intraocular pressure over or equal 21 mm Hg are advised to orally take two capsules containing a total of 500 mg of Cordyceps cicadae mycelia. After 90 minutes, the subjects are evaluated for intraocular pressure.

The pre-test and and post-intake intraocualr pressure and blood pressure data will be compared by paired t test for significant differences if any.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 20 and 75 years old, regardless of gender.
  • Pre-test confirmation of high intraocular pressure.
  • Subjects should understand the trial and agree to join the project.

Exclusion criteria

  • Age under 20 or over 75 years.
  • Use intraocular pressure lowering drugs other than Taflotan (saflutan).
  • Using beta-blockers or diuretics.
  • Being pregnant.
  • Disabled individuals with specific diseases or malfunction, for example tumours at terminal stage, blindness.
  • Loss of self-consciousness and behavioral capacity.
  • Patients with major diseases.

Withdrawal criteria All subjects may withdraw at any time without any reason. The act of withdraw does not affect rights for them to seek medical advice or treatments.

Treatment and study plan

Cordyceps Cicadae Mycelia

Dietary Supplement

Cordyceps Cicadae Mycelia will be given to test its potential for alleviation of high intraocular pressure.

Primary outcomes

  1. Intraocular pressure

    Time frame: 0 minutes (before given Cordyceps Cicadae Mycelia)

    Intraocular pressure of both eyes will be assessed

  2. Intraocular pressure

    Time frame: 90 minutes after given Cordyceps Cicadae Mycelia

    Intraocular pressure of both eyes will be assessed

  3. Blood pressure

    Time frame: 0 minutes (before given Cordyceps Cicadae Mycelia)

    Both systolic and diastolic blood pressures will be assessed

  4. Blood pressure

    Time frame: 90 minutes after given Cordyceps Cicadae Mycelia

    Both systolic and diastolic blood pressures will be assessed

Sponsors and collaborators

Lead sponsor

Han-Hsin Chang

Other

Collaborators

  • Grape King Bio Ltd.

Registry information

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Mar 31, 2022
Registry last updated
Mar 31, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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