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Completed

NCT Number: NCT00607412

Alcohol Use Disorders (AUDs) and Post-traumatic Stress Disorder (PTSD) Treatment for Victims of Partner Violence

The goal of this study is to evaluate a psychotherapy for PTSD and substance use disorders among women who have experienced domestic violence. The hypothesis is that women who receive present-focused, integrated treatment will have greater PTSD symptom reduction and have less substance use after treatment than women in the control condition who will receive supportive therapy based on a 12-step approach.

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Key information

Conditions

PTSD Chemically-Induced Disorders Mental Disorders Stress Disorders, Post-Traumatic Stress Disorders, Traumatic Substance Use Disorders Substance-Related Disorders Trauma and Stressor Related Disorders

Age range

18 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Phase 2

Primary location

UCSD Outpatient Psychiatry

San Diego, California, 92103, United States

About this study

The goal of this study is to evaluate an integrated psychotherapy for PTSD and substance use disorders among female victims of intimate partner violence. The hypothesis is that women who receive present-focused, integrated treatment will have greater PTSD symptom reduction and have less substance use post-treatment than women in the control condition who will receive supportive therapy based on a 12-step approach.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • female victims of partner violence
  • at least one month out of the abusive relationship
  • meet DSM-IV (American Psychiatric Association, 1994) criteria for PTSD and an alcohol use disorder
  • literate in English
  • have not changed psychotropic medications or dosages within the past two months and agree not to during the active phase (first 12 weeks) of the intervention
  • have an identified primary care physician

Exclusion criteria

  • moderate or severe cognitive impairment as measured by a Mini-Mental State Examination score less than or equal to 18
  • Histories of psychosis or mania may be excluded because the presence of these disorders is thought to impede progress in psychotherapy

Treatment and study plan

Integrated psychotherapy for PTSD and substance use

Behavioral

integrated, present focused psychotherapy for PTSD and substance use disorders tailored to women who have experienced intimate partner violence

12-step based supportive therapy

Behavioral

supportive psychotherapy based on 12-step model

Primary outcomes

  1. CAPS for PTSD symptoms and ASI for substance use

    Time frame: pre, mid treatment, post, 3-month follow-up, 6-month follow-up

Secondary outcomes

  1. Timeline Follow-back procedure, Beck Depression Inventory

    Time frame: same as primary

Sponsors and collaborators

Lead sponsor

University of California, San Diego

Other

Registry information

Official study title

AUDs and PTSD Treatment for Victims of Partner Violence

Important dates

Study start
2007
Primary completion
2011
Study completion
2011
First posted
Feb 5, 2008
Registry last updated
May 11, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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