Alcohol Effects on Driving-related Skills of Young Drivers

This study will examine the effects of an intoxicating dose of alcohol on driving-related skills among young drivers using driving simulator technology.

This study is a double-blind, placebo-controlled mixed design study, including randomized between-subjects comparison of the effects of alcohol intoxication and both between- and within-subjects examination of acute and residual effects at approximately 24 and 48 hours following one-time alcohol administration.

Initial contact with potential participants will be made by telephone, where study personnel will conduct a telephone screen for eligibility. Those telephone screened as eligible will attend CAMH for an eligibility assessment. Enrolled participants will complete four sessions on consecutive days: a practice day, an alcohol administration day, and a 24-hour and 48-hour post-alcohol session.

Inclusion criteria

• Males and females aged 19 to 25.
• Reported consumption of at least 1 heavy drinking episode (according to NIAAA criteria of 5 drinks for males and 4 for females within an occasion) in the 6 months prior to eligibility assessment.
• Held a valid class G or G2 Ontario driver's license (or equivalent from another jurisdiction) for at least 12 months.
• Willing to abstain from alcohol use for the duration of the study, and for 48 hours prior to Session 2.
• Provides written and informed consent.

Exclusion criteria

• Taking medications or have any medical condition for which alcohol is contraindicated
• Is a regular user of medications that affect brain function (i.e., antidepressants, benzodiazepines, stimulants).
• Diagnosis of severe medical or psychiatric conditions.
• Meets criteria for current or lifetime Substance Use Disorders (DSM-IV) with the exception of nicotine.
• Meets criteria for Alcohol Dependence (DSM-IV)
• Is pregnant, is trying to become pregnant, or is currently breastfeeding.
• Severe allergic reaction to citrus.