NCT Number: NCT06322537
All heart surgery patients universally require hydration, which is given through a vein in the arm, but practices for treating patients are not universal. There are disagreements about whether crystalloids should be used alone or in combination with albumin. This question has important implications because albumin is an expensive blood product in relatively limited supply, and 20% of its use is by heart surgery patients. The goal of this study is to learn more about how crystalloids and albumin are used during heart surgery, as well as, key patient outcomes.
This study is active but is not currently recruiting participants.
Notify Me18 year–99 year
All sexes
Observational
Royal Columbian Hospital, New Westminster, British Columbia, Canada
The goal of this proposed multicentre retrospective cohort study is to characterize perioperative usage patterns of crystalloids and albumin, as well as key patient outcomes, in cardiac surgical patients. This study will also address numerous other knowledge gaps in the area of perioperative blood product management and fluid administration in cardiac surgery and define a collaborative group to support future research in this field.
The primary objective is to obtain granular information on if, when, and how albumin is given perioperatively to cardiac surgical patients. This includes the doses and settings in which albumin is used, the types of crystalloid solutions (balanced or unbalanced) used, and when albumin is used (for example, while on cardio-pulmonary bypass, in the ICU, or on the ward) in perioperative cardiac surgical care across institutions. This important information about the scope of albumin and crystalloid use across the country will inform the design of our future intervention and control arms in the planned definitive trial.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: On CPB, in the operating room but not during CPB, in the ICU, on the ward to post operative day 28.
Type, dose and timing of administration, the setting in which it was ordered, indication for use, and the type of provider responsible for the patient at administration (surgeon, anesthesiologist, intensivist, nurse practitioner).
Time frame: On CPB, in the operating room but not during CPB, in the ICU, on the ward to post operative day 28.
Type and volume of crystalloid given (Normal saline, Ringer's Lactate, Plasmalyte-148, and others), as well as the setting of administration will be recorded.
University Health Network, Toronto
Other
Albumin Utilization for Intravascular Volume Replacement in Adult Cardiac Surgical Patients : A Multi-centre, Retrospective, Cohort Study
Acronym: AlbACS-1R
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06752980
Cardiovascular Surgical Procedures, Confusion
Selçuklu, Konya, Turkey (Türkiye)
View Trial DetailsNCT07557108
Agnosia, Cardiovascular Diseases
Ordu, Altinordu, Turkey (Türkiye)
View Trial DetailsNCT07386379
Cardiovascular Surgical Procedures, Nausea
Istanbul, Outside of the US, Turkey (Türkiye)
View Trial DetailsNCT07348328
Cardiovascular Surgical Procedures, Major Adverse Cardiovascular Events (MACE)
Shanghai, DR, China
View Trial Details