Seattle Children's Hospital
Seattle, Washington, 98105, United States
NCT Number: NCT03538769
Acute kidney injury (AKI) is a common clinical event with severe consequences. In the United States alone, greater than one million hospitalized patients per year are diagnosed with AKI. It has been independently associated with prolonged hospital stays, 25-80% risk of in-hospital death, and future progression to chronic kidney disease. While there has been an increase in awareness about the prevalence and significance of AKI, studies have uncovered systematic failure in the management of AKI, largely relating to the failure of clinicians to recognize and manage the condition appropriately. This is where we can use electronic health records (EHRs) and electronic alerts (e-alerts) to our advantage. In this study, the investigators plan to use e-alerts integrated into a clinical decision support (CDS) system to improve the care of and outcomes of patients with AKI. The aims are to study the prevalence of AKI and its progression among hospitalized patients using an 'AKI sniffer' (an EHR based automated system) and to prospectively study if introducing a complex intervention (an e-alert combined with a clinical decision support system) will reduce progression of AKI in children. The investigators have developed an AKI care bundle which provides simple guidelines for management of AKI along with specific discharge instructions to improve follow up care. The primary outcome is AKI progression. Secondary outcomes include morbidity, mortality, length of hospital stay, need for renal replacement therapy, and recovery of renal function by time of hospital discharge. The investigators will also look at documentation of AKI and if these participants get appropriate follow up.
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Notify Me6 month–18 year
All sexes
Interventional
Not applicable
Seattle, Washington, 98105, United States
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
All patients between 6 months-18 years admitted to the surgical and medical floors of Seattle Children's Hospital
Exclusion criteria
Providers taking care of patients will receive an electronic alert and will be guided to use a clinical decision support system
Time frame: 28 days
Documentation of AKI in progress notes and discharge summary
Time frame: 7 days
Progression of AKI from Stage 1 to Stage 2/3
Seattle Children's Hospital
Other
Acute Kidney Injury: Integrating E-alerts and Clinical Decision Support System to Improve Outcomes
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