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NCT Number: NCT01555411

Akershus Cardiac Examination (ACE) 1950 Study

Akershus Cardiac Examination (ACE) 1950 Study is a large, observational, prospective, longitudinal, population-based cohort study. The overall aim is to establish an extensive cardio- and cerebrovascular age cohort of elderly subjects for various longitudinal long-term follow-up studies of cardiovascular and cerebrovascular disease.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Atrial Fibrillation Arrhythmias, Cardiac Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Cognition Disorders Cognitive Dysfunction Heart Diseases Heart Failure Mental Disorders Mild Cognitive Impairment Nervous System Diseases Neurocognitive Disorders Pathologic Processes Pathological Conditions, Signs and Symptoms Vascular Diseases

Age range

62 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Akershus University Hospital, Lørenskog, Akershus, Norway

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About this study

Design: The Akershus Cardiac Examination (ACE) 1950 Study is a population-based, prospective, cerebro- and cardiovascular age-cohort study of all men and women born in 1950 in Akershus County, Norway.

Time schedule: Study inclusion and baseline examinations took place in the period September 2012 - May 2015.

Current status: 10-year follow-up examinations of all participants are undertaken in 2023-2025, and sub-studies are ongoing.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Resident in Akershus County (as per October 2011, prior to study invitation)
  • Born in the year of 1950
  • Ability to consent to participation

Treatment and study plan

Primary outcomes

  1. Outcomes related to CVD and CV-associated conditions

    Time frame: Maximum 35 years

Secondary outcomes

  1. Specific CV endpoints; e.g. acute myocardial infarction, heart failure, atrial fibrillation, etc.

    Time frame: Maximum 35 years

  2. Specific CV-associated conditions, including renal, cerebrovascular, pulmonary, etc.

    Time frame: Maximum 35 years

  3. Specific clinical phenotypes; e.g. myocardial and arterial structure and function, lung function, etc.

    Time frame: Maximum 35 years

Other outcomes

  1. Impact of left atrial size and function measurements by echocardiography on stroke risk in an 62-65-year-old cohort

    Time frame: Within 35 years

  2. Relation between cognitive function and sub-clinical CVD in a 62-65-year-old Norwegian population cohort

    Time frame: Maximum 35 years

Sponsors and collaborators

Lead sponsor

Vestre Viken Hospital Trust

Other

Collaborators

  • University Hospital, Akershus

Registry information

Official study title

Akershus Cardiac Examination 1950 Study - a Cohort Study on Cardio- and Cerebrovascular Disease in 62-65-year-old Subjects

Acronym: ACE1950

Important dates

Study start
2012
Primary completion
2050
Study completion
2050
First posted
Mar 15, 2012
Registry last updated
May 8, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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