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NCT Number: NCT07453563

Airway Scope vs GlideScope for Intubation in Obese Patients

This study compares the time required to complete intubation in obese patients (Body Mass Index 40 or greater) when using either the GlideScope or Airway Scope video laryngoscope device to help place the endotracheal tube.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of New Mexico Health Sciences Center

Albuquerque, New Mexico, 87131, United States

Location contact

Yuta Kashiwagi, MD

CONTACT

[email protected]

505-272-2610

About this study

This is a randomized controlled trial of two video laryngoscope devices when used in patients with high (≥40) Body Mass Index (BMI): Airway Scope (Nihon Kohden) and GlideScope (Verathon Inc.). The study compares several outcomes as proxies for ease of intubation including time to complete intubation, number of attempts needed, minimum peripheral oxygen saturation (SpO2) during intubation, and number of episodes of SpO2 falling below 90% before intubation is completed. The patient population is consenting adult patients with BMI ≥40, who are already scheduled for general anesthesia. Intubations will be performed by attending anesthesiologists or anesthesiology residents. Obesity is a known risk factor for difficult intubation due to anatomical changes caused by increased soft tissue around the face and neck. Obese patients' blood oxygen level can rapidly fall during intubation because these patients often have reduced functional residual capacity, and the acuity of any complications may also be increased because these patients also often have additional comorbidities.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult (age ≥18 years)
  • Body Mass Index (BMI) ≥40
  • Scheduled for surgery with general anesthesia

Exclusion criteria

  • Pregnancy
  • Congenital facial or airway anomalies
  • History of major neck surgery or tracheostomy
  • History of any lung diseases/conditions such as Chronic Obstructive Pulmonary Disease, lung resection, or lung cancer
  • History of cardiac failure or myocardial infarction
  • Prisoners

Treatment and study plan

Intubation with GlideScope

Device

Intubation performed by anesthesiologist using the GlideScope video laryngoscope device

Intubation with Airway Scope

Device

Intubation performed by anesthesiologist using the Airway Scope video laryngoscope device

Primary outcomes

  1. Intubation completion time

    Time frame: Perioperative/Periprocedural

    Time interval between the start of the intubation procedure and its completion, defined by confirmed end-tidal carbon dioxide (CO2) observation.

Secondary outcomes

  1. Humber of hypoxia episodes

    Time frame: Perioperative/Periprocedural

    The number of episodes of hypoxia during the intubation procedure, defined as peripheral oxygen saturation (SpO2) <90%.

  2. Number of intubation attempts

    Time frame: Perioperative/Periprocedural

    The count of attempts required to complete the intubation procedure, with completion defined as confirmed end-tidal CO2

  3. Minimum SpO2 observed during intubation

    Time frame: Perioperative/Periprocedural

    The minimum value of SpO2 observed during the intubation procedure

Study contacts

Contact information is provided by the study sponsor or research team.

Yuta Kashiwagi, MD

CONTACT

[email protected]

505-272-2610

Sponsors and collaborators

Lead sponsor

University of New Mexico

Other

Registry information

Official study title

Comparison of GlideScope and Airway Scope for Intubating Morbidly Obese Patients: A Randomized Controlled Study

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Mar 6, 2026
Registry last updated
May 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.