Airflow Perturbation Device (APD) for the Evaluation of Pulmonary and Sleep Disorders

In a prospective, observational study the investigators compared resistance values measured using the airway perturbation device (APD) to impulse oscillometry and spirometry. The investigators also created reference equations for normal APD resistance ranges using the data from clinically normal volunteers.

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Key information

Conditions

Airway Obstruction Respiration Disorders Respiratory Insufficiency Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Male and female subjects > 18 years
Referred for PFTs and/or PSG at WRNMMC
All races and ethnicities will be included
Pregnant women will be included

Exclusion criteria

< 18 years of age
If mental status is questionable, the patient will be excluded at the discretion of the consenting provider
Unable/unwilling to follow the directions necessary for APD use

Treatment and study plan

Airflow pertubation device

Diagnostic Test

Participants have airway resistance measured at the mouth by tidal breathing into a mouth-piece connected to the airflow perturbation device.

Other names: APD

Primary outcomes

Number of participants with APD correlation > 0.5 with spirometry

Time frame: At enrollment

Respiratory resistance ( cm H20/L/s) measured with APD correlated with volumes (in liters) measured by spirometry.

Secondary outcomes

Number of participants with APD correlation > 0.5 with impulse oscillometry

Time frame: At enrollment

Respiratory resistance (cm H20/L/s) measured with APD correlated with resistance (cm H20/L/s) measured using impulse oscillometry

Sponsors and collaborators

Lead sponsor

Walter Reed National Military Medical Center

Fed

Registry information

Important dates

Study start: 2013
Primary completion: 2014
Study completion: 2014
First posted: Feb 15, 2017
Registry last updated: Feb 23, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed