Skip to main content
OpenTrials
Completed

NCT Number: NCT03904875

Air Pollution and COPD Exacerbation

There is an excess of hospitalization rates for acute exacerbation of COPD in Picardy compared to the national data. A first study realized in Picardy has shown a link between air quality and COPD. Nevertheless, the particles type is unknown and according to it, impact on COPD could be different. The investigator goal is to find a correlation between acute exacerbation of COPD consultation rate and daily ultra thin particles in Haut de France. The investigators will correlate the particles composition with daily acute exacerbation of COPD rate. All COPD patients with a diagnosis of acute exacerbation in emergency room in University Hospital of Amiens-Picardie and Lille, and Clinique de l'Europe between 01/01/2020 and 31/12/2020 will be included. For each patient, home and work address will be collected. The duration of 1 year was chosen to take into account seasonal variations. In parallel, a daily report of the rate of ozone, particles (PM2.5 and PM10), dioxide nitrogen but also odours and pollens will be done by ATMO Haut de France.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Pollution; Exposure Chronic Disease Chronic Obstructive Pulmonary Disease Disease Attributes Lung Diseases Lung Diseases, Obstructive Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU Amiens

Amiens, 80480, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • COPD patients with a diagnosis of acute exacerbation of COPD in the emergency room of Amiens and Lille centers
  • Adults
  • Patients able to express consent
  • signed written informed consent form
  • covered by national health insurance

Exclusion criteria

  • patients non covered by national health insurance
  • patients not able to express consent
  • minors

Treatment and study plan

collection of data about each acute exacerbation of COPD

Other

COPD is chronic obstructive pulmonary disease. Data collected are need of hospitalisation, final diagnosis, home address, work address and air quality data.

Primary outcomes

  1. daily rate of COPD exacerbation consultation in the emergency room of the 3 centers

    Time frame: every day during 12 months

    daily rate of COPD exacerbation consultation in the emergency room of the 3 centers

  2. ultrathin particles quantity in the air

    Time frame: every day during 12 months

    ultrathin particles quantity will be determined by the air of "Haut de France" by the company ATMO Haut de France.

Secondary outcomes

  1. chemical composition ultrathin particles

    Time frame: every day during 12 months

    chemical composition ultrathin particles will be determined by the air of "Haut de France" by the company ATMO Haut de France.

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire, Amiens

Other

Collaborators

  • Clinique de l'Europe, Amiens
  • University Hospital, Lille

Registry information

Official study title

Impact of Air Pollution on Chronic Obstructive Pulmonary Disease (COPD) Exacerbation in Haut de France. BePoPi Project.

Acronym: BePoPi

Important dates

Study start
2020
Primary completion
2022
Study completion
2023
First posted
Apr 5, 2019
Registry last updated
Sep 13, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.