Air Pollution and Cardiovascular Disease

To determine the effects of ambient airpollution exposures on cardiovascular responses among healthy adults without cardiovascular disease.

Completed

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Key information

Conditions

Metabolic Disorder Metabolic Diseases Nutritional and Metabolic Diseases

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

without CV disease or risk factors (e.g., hypertension, diabetes, or treated hyperlipidemia). Subjects are non-smokers in non-smoking household.

Exclusion criteria

Screening visit BP>140/90 mm Hg, fasting glucose >126 mg/dL, or positive urine pregnancy test (females). Subjects cannot be taking any medications or over-the-counter drugs that affect CV function.

Treatment and study plan

Primary outcomes

Dyslipidemia

Time frame: One year

Analyzed HDL by Beckman AU5800

Secondary outcomes

System oxidative stress

Time frame: One year

Analyzed oxidative stress biomarkers,such as MDA by HPLC

Sponsors and collaborators

Lead sponsor

WeiHuang

Other

Registry information

Important dates

Study start: 2014
Primary completion: 2016
Study completion: 2016
First posted: Oct 9, 2015
Registry last updated: Jul 12, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed