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OpenTrials
Completed

NCT Number: NCT06179693

AIMN Multicenter Study: Staging of Lymphomas Using PET/CT

In recent years, the introduction of PET/CT tomographs (which have now almost completely replaced tomographs equipped with PET alone), has allowed a significant increase in diagnostic accuracy in the majority of tumors. However, in order to reduce the radiation doses, administering CT images are acquired for patients at a low dose (generally 60mA 120kV) without the use of contrast agents. This prudential attitude, however, makes it essential to carry out "diagnostic" CT investigations which, at the end of the diagnostic process It leads to an increase in the dose administered for the patient rather than to savings.

This study aims to evaluate the possible advantages in diagnostic, economic and quality of life terms of PET/CT performed with diagnostic CT with intravenous contrast medium, with the aim of benefiting the neoplastic patient in the diagnostic process by optimizing (from a temporal and dosimetric point of view ) the diagnostic procedures to which it is subjected.

It is expected that the integrated PET/CT procedure can facilitate the process of staging the neoplasm and that this procedure can have a positive impact on the patient's quality of life while also reducing the costs incurred in terms of time and money.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Irccs San Raffaele

Milan, Italy

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Established lymphoma (non-Hodgkin's lymphoma and Hodgkin's disease) being staged;
  • Performing the PET/CT examination within two weeks of diagnosis and before treatment;
  • Signing of the Informed Consent.

Exclusion criteria

  • patients <18 years;
  • Patients who have not signed the Informed Consent;
  • Execution of previous anti-inflammatory or anti-inflammatory therapies in the 4 weeks preceding the PET exam.

Treatment and study plan

Diagnostic accuracy

Diagnostic Test

As per standard procedure, patients will undergo FDG PET. Following the PET exam it will be acquired a standard CT with intravenous contrast medium, using the CT tomograph inserted inside the PET one.

Primary outcomes

  1. PET/CT with contrast medium in a single session to diagnosis of patients with malignant limphoma.

    Time frame: 2 years

Sponsors and collaborators

Lead sponsor

IRCCS San Raffaele

Other

Registry information

Important dates

Study start
2009
Primary completion
2011
Study completion
2011
First posted
Dec 22, 2023
Registry last updated
Dec 22, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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