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NCT Number: NCT06570070

AI-powered Chatbot vs. Human Counselors in Smoking Cessation

This study aims to explore the feasibility and preliminary effectiveness of AI-powered chatbot support in community smokers.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Beijing Normal University

Zhuhai, Guangdong, 519087, China

Location contact

Xue Weng

CONTACT

[email protected]

About this study

Smoking cessation remains one of the most significant public health challenges worldwide, with tobacco use being a leading cause of preventable death and disease. Despite extensive efforts, the success rates of smoking cessation programs remain low, necessitating innovative approaches to support individuals in their journey to quit smoking. Recently, artificial intelligence (AI) has opened new possibilities in healthcare, including the development of AI-powered chatbots that assist individuals in behavior change, such as quitting smoking.

This randomized controlled trial aims to investigate the effectiveness of AI-powered chatbot that simulates human counselors, compared to traditional human counseling in promoting smoking cessation among community smokers. The AI-powered chatbot, equipped with personalized interactions and real-time support, offers scalable and cost-effective assistance, potentially making it an accessible alternative to human counseling. However, human counselors provide empathy, tailored advice, and a nuanced understanding of human behavior that AI may not fully replicate. This study will explore which approach is more effective in helping individuals achieve long-term smoking cessation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • aged 18 and above, reside in Zhuhai for the next 6 months;
  • smoke at least 1 cigarette or use e-cigarettes daily;
  • Having a smartphone and a WeChat account, being able to use WeChat skillfully.

Exclusion criteria

  • Smokers who have communication barrier (either physically or cognitively);
  • Smokers who are currently participating in other SC programmes or services

Treatment and study plan

5A's/5R's advice

Behavioral

5A's (Ask, Advise, Assess, Assist, Arrange) for smokers who are ready to quit, and 5R's (relevance, risks, rewards, roadblocks, and repetition) for smokers who are not ready to quit.

Brief leaflet on health warning and smoking cessation

Other

The contents of the leaflet include the absolute risk of smoking, diseases caused by active and second-hand smoking, horrible pictorial warnings of the health consequences of active and second-hand smoking, and the benefits of quitting.

Self-help smoking cessation booklet

Other

The contents include information about the benefits of quitting, methods to quit, how to handle withdrawal symptoms, misperceptions of quitting, etc.

AI-powered chatbot support

Behavioral

Participants will receive three months of AI-powered chatbot, equipped with personalized interactions and real-time support, via WeChat.

Counselor individual support

Behavioral

Participants will receive three months of counselor-led individual support via WeChat. The regular messages and instant messaging on psychosocial support aim to provide cessation advice, increase self-efficacy and confidence, and social support and behavioral capacity of quitting.

Primary outcomes

  1. Biochemical validated quit rate at 6 months follow-up

    Time frame: 6 months follow-up

    The primary outcomes are biochemically validated quit rate (exhaled carbon monoxide < 4 ppm or salivary cotinine < 30 ng/ml)

Secondary outcomes

  1. Biochemical validated quit rate at 3 months follow-up

    Time frame: 3 months follow-up

    biochemically validated quit rate (exhaled carbon monoxide < 4 ppm or salivary cotinine < 30 ng/ml)

  2. Self-reported 7-day point prevalence quit rate

    Time frame: 3 and 6 months follow-up

    Self-reported 7-day point prevalence quit rate in the two groups

  3. Smoking reduction rate

    Time frame: 3 and 6 months follow-up

    Rate of smoking reduction by at least half of baseline amount in the two groups

  4. Eligibility rate

    Time frame: baseline

    the percentage of eligible smokers out of the total number of smokers screened

  5. Consent rate

    Time frame: baseline

    the percentage of eligible smokers who agree to participate out of the total number of eligible smokers

  6. Percentage of Participant Engagement with E-Messages and Counselor Chats

    Time frame: 3 months follow-up

    This outcome measures the percentage of participants who engage with the intervention by reading e-messages and responding to counselor chat messages at least once during the 3-month follow-up period.

Study contacts

Contact information is provided by the study sponsor or research team.

Xue Weng

CONTACT

[email protected]

3621259

Sponsors and collaborators

Lead sponsor

Beijing Normal University

Other

Registry information

Official study title

Effectiveness of Artificial Intelligence (AI)-Powered Chatbot vs. Human Counselors in Smoking Cessation

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Aug 26, 2024
Registry last updated
Aug 26, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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