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OpenTrials
Completed

NCT Number: NCT07157085

AI Multitask Model for HCC Treatment

We will integrate multi-modal cardiac data via an AI multitask framework to develop and validate concurrent models for liver function, treatment prognosis, and microvascular invasion (MVI) prediction in hepatocellular carcinoma. The resulting tool will be prospectively deployed to guide personalized surgical, TACE, and systemic therapy decisions.

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Key information

Conditions

Hepatocellular Carcinoma (HCC) Adenocarcinoma Carcinoma Carcinoma, Hepatocellular Digestive System Diseases Digestive System Neoplasms Liver Diseases Liver Neoplasms Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Glandular and Epithelial

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Guangzhou, Guangdong, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age 18-75 years;
  • HCC diagnosed according to the European Association for the Study of the Liver/American Association for the Study of Liver Diseases criteria)
  • Eastern Cooperative Oncology Group performance status < 2;
  • Child-Pugh class A or B liver function;

Exclusion criteria

  • HCC combined with other malignancies;
  • missing image data during perioperative period;
  • lost to follow-up > 12 months.

Treatment and study plan

comprehensive treatment

Other

Comprehensive HCC therapies include liver resection, TACE, HAIC, targeted therapy, immunotherapy and radiotherapy

Primary outcomes

  1. Overall Survival

    Time frame: 60 months

    from diagnosis of HCC to death or last follow-up

Secondary outcomes

  1. Progression-free survival

    Time frame: 60 months

    from diagnosis of HCC to disease progression or last follow-up

Sponsors and collaborators

Lead sponsor

Sun Yat-sen University

Other

Registry information

Official study title

AI-Driven Multitask Model for Guiding Treatment Decision-Making in Hepatocellular Carcinoma

Important dates

Study start
2008
Primary completion
2023
Study completion
2023
First posted
Sep 5, 2025
Registry last updated
Sep 5, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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