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NCT Number: NCT06996873

Aggressive Spinal Hemangioma

This research is a case series analysis to evaluate aggressive vertebral hemangiomas. It focuses on clinical presentation, diagnostic imaging accuracy (X-ray, MRI, MSCT, angiography), and treatment efficacy. The primary goal is to establish optimal management protocols.

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Key information

Conditions

Aggressive Spinal Hemangiomas Hemangioma Neoplasms Neoplasms by Histologic Type Neoplasms, Vascular Tissue

Sex eligibility

All sexes

Study type

Observational

About this study

Hybrid methodology integrating retrospective case reviews (from Assiut University Hospital's Orthopedic Surgery Department) with synthesis of existing literature.

Objectives:

Characterize clinical presentations and imaging findings. Compare diagnostic accuracy across modalities. Analyze treatment outcomes, including procedural success rates and complications.

Tools:

Imaging: X-ray for initial screening, MRI/MSCT for soft tissue and spinal cord involvement, angiography for vascular mapping.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients diagnosed with aggressive spinal hemangiomas based on clinical symptoms and imaging findings.
  • Cases confirmed through diagnostic modalities such as X-ray, MRI, MSCT, or angiography.
  • Patients presenting with symptoms such as pain, neurological deficits, or spinal instability attributable to the hemangioma.

Exclusion criteria

  • Patients with incidentally discovered spinal hemangiomas (asymptomatic cases found during evaluations for unrelated conditions).
  • Cases lacking sufficient diagnostic evidence to confirm aggressive spinal hemangioma.

Treatment and study plan

Primary outcomes

  1. Neurological Symptom Resolution

    Time frame: 3 months

    using the Pain intensity (VAS scale)

Secondary outcomes

  1. Functional Status Improvement

    Time frame: 3 months

    using ASIA Impairment Scale (primary)

    Threshold: ≥1-grade improvement on ASIA scale sustained for ≥3 months

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Management Of Aggressive Spinal Hemangioma

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
May 30, 2025
Registry last updated
May 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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