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Completed

NCT Number: NCT03269656

Age Gene/Environment Susceptibility Reykjavik Study

5764 men and women in Iceland, aged 66 to 96 years entered the Ages Gene/Environment Susceptibility (AGES) - Reykjavik Study. Serum 25(OH)D was measured in 5,519 of all 5,764 (96%) participants at study entry in year 2002 through 2006. The main emphasis was on exploring whether pre-diagnostic serum levels of 25(OH)D were associated with survival after cancer diagnosis.

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Key information

Conditions

Age range

66 year–98 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • To participate in the AGES-Reykjavik study

Exclusion criteria

  • To be diagnosed with cancer before study entry

Treatment and study plan

Primary outcomes

  1. Overall survival

    Time frame: From date of diagnosis until death or censored at end of the follow-up (December 31, 2014)

    The association between pre-diagnostic 25(OH)D levels in cancer patients and overall survival

  2. Cancer survival

    Time frame: From date of diagnosis until cancer death or censored at the end of the follow-up (December 31, 2014)

    The association between pre-diagnostic 25(OH)D levels in cancer patients and cancer survival

Secondary outcomes

  1. Cancer diagnosis

    Time frame: From date of blood draw (study entry) until cancer diagnosis, death or end of the observation period (December 31, 2014) whichever occurred first

    The association between pre-diagnostic 25(OH)D levels and cancer risk

Sponsors and collaborators

Lead sponsor

Icelandic Heart Association

Other

Collaborators

  • University of Iceland

Registry information

Official study title

Association of Pre-diagnostic Vitamin D Levels and Survival in Older Individuals With Cancer

Acronym: AGES

Important dates

Study start
2002
Primary completion
2006
Study completion
2014
First posted
Sep 1, 2017
Registry last updated
Sep 1, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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