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OpenTrials
Completed

NCT Number: NCT01106742

Agaricus Blazei Murill (ABM) in Patients With Inflammatory Bowel Disease (IBD)

Based on the anti-inflammatory and stabilising effect of the AbM, (Agaricus Blazei Murill) based mushroom extract AndoSanTM on cytokine release in blood in vivo and ex vivo in healthy volunteers after 12 days consumption, the aim in this study is to investigate whether same effect is valid in patients with IBD (inflammatory bowel disease). In addition, calprotectin an abundant cytosolic protein in neutrophils and a surrogate marker for degree of intestinal inflammation will be measured in blood and feces of these patients.

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Key information

Conditions

Inflammatory Bowel Disease Digestive System Diseases Gastroenteritis Gastrointestinal Diseases Inflammatory Bowel Diseases Intestinal Diseases

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Oslo University Hospital, Department of Surgery

Oslo, 0407, Norway

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Moderate disease activity

Exclusion criteria

  • No use of Imurel (Azathioprin) or anti-TNF treatment

Treatment and study plan

AndoSan

Dietary Supplement

AndoSan, 20mlx3, 12 days

Other names: Agaricus blazei Murill

Primary outcomes

  1. The ultimate goal is to see whether the ABM can be used as additional treatment of IBD.

    Time frame: 12 days

Sponsors and collaborators

Lead sponsor

Ullevaal University Hospital

Other

Registry information

Official study title

Potential Anti-inflammatory Effect of Mushroom Extract From Agaricus Blazei Murill (ABM) in Patients With Inflammatory Bowel Disease (IBD)

Important dates

Study start
2009
Primary completion
2011
Study completion
2011
First posted
Apr 20, 2010
Registry last updated
Jul 19, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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