CHU Bordeaux - hôpital Pellegrin
Bordeaux, 33000, France
NCT Number: NCT01517789
Visual morbidity (visual acuity and/or visual field deficit) must be taken into account during neurosurgical procedures for lesions near the optical pathways. Part of this morbidity is due to surgical manipulation. There is no validated tool for intraoperative visual monitoring and few publications have studied this issue.
In a preliminary work based on analysis of these publications, we defined technical, anaesthetic and analytical parameters in order to optimise intraoperative visual evoked potentials monitoring. These parameters are special devices used for transpalpebral stimulation, complete intravenous anaesthesia without halogen or nitrous oxide, and pertinent analysis criteria of visual evoked potential (VEP). We suppose that these improvements will increase reliability of intraoperative VEP.
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Notify Me13 year and older
All sexes
Interventional
Not applicable
Bordeaux, 33000, France
This genuine optimised monitoring in France, set up in association with Metrovision company, should help increasing intraoperative VEP reliability as a monitoring tool for visual pathways function.
In this study, we assess the predictive value of relevant intraoperative variations of VEP (more than 50% variation of latency and amplitude) on the visual prognosis at six months after surgery The visual assessment consisting of a visual field, a visual acuity, and the performance of pattern transient VEP, will be performed by an ophthalmologist before surgery, and at three and six months after surgery. An electroencephalogram with photostimulatory lighting will be used in pre-operative and will validate the absence of photo-induced epilepsy risk.
During the intervention, VEPs associated to an electroretinogram will be performed by a neurosurgeon trained to the use of these tools by Metrovision company:
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Visual assessment (visual field, visual acuity, pattern visual evoked potential) are realised before and after surgery.
Flash and steady state visual evoked potential are measured during the surgical procedure at different times.
Time frame: Month 6 after surgery
Visual function : visual field and visual acuity six months after surgery.
Time frame: Month 6 after surgery
Time frame: Month 6 after surgery
Time frame: Month 6 after surgery
University Hospital, Bordeaux
Other
Acronym: VISUOPEV
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