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OpenTrials
Completed

NCT Number: NCT00680576

Adolescent Substance Abuse: Progressive Treatment

The purpose of this study is to find out more about how to provide effective further treatment for adolescents who have received six weeks of group therapy for substance-use problems and continue to use drugs. Treatments used in the study include a group therapy (MET/CBT), an individual therapy (CBT), and a family therapy (FFT). The study will look at whether abstinence or a very low level of use is a better guide for deciding whether further treatment is needed, how well different combinations of treatment work to reduce substance use, and whether it is possible to predict in advance which adolescents will respond best to which types of treatment. Study investigators expect that a treatment strategy using what is learned about these issues in the first half of the project to develop an "adaptive" treatment model will work better than a "fixed" treatment to reduce adolescent substance use.

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Key information

Conditions

Substance Abuse Chemically-Induced Disorders Mental Disorders Substance-Related Disorders

Age range

13 year–18 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Oregon Res. Inst. Center for Family & Adolescent Research (CFAR)

Albuquerque, New Mexico, 87102, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 13 to 18 years if age
  • Meet DSM-IV (APA, 1994) diagnostic criteria for substance abuse or dependence
  • Live in the Albuquerque metropolitan area or surrounding communities
  • Sufficient residential stability to permit probable contact at follow-up (e.g., not homeless at time of intake).

Exclusion criteria

  • There is evidence of psychotic or organic state of sufficient severity to interfere with the understanding of study instruments and procedures
  • The adolescent is deemed dangerous to self or others during evaluation
  • Services other than outpatient treatment are required for the adolescent (e.g., inpatient, detoxification)
  • Marijuana use is reported as being less than 13% of days in the previous 90 days.

Treatment and study plan

CBT, Cognitive Behavioral Therapy

Behavioral

Eight weekly sessions of individual Cognitive Behavioral Therapy, to develop skills enabling adolescents stop or reduce their drug use.

FFT, Family Functional Therapy

Behavioral

Eight weekly sessions of Functional Family Therapy designed to strengthen family relationships and build skills to help the adolescent stop or reduce his/her drug use.

Primary outcomes

  1. Urine drug screens

    Time frame: Pretx, 6, 14 and 22 weeks, 3 and 6 months after initial treatment session

Sponsors and collaborators

Lead sponsor

Oregon Research Institute

Other

Registry information

Acronym: ADAPT

Important dates

Study start
2008
Primary completion
2013
Study completion
2013
First posted
May 20, 2008
Registry last updated
Oct 10, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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