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NCT Number: NCT07094503

Adolescent Chatbot

The purpose of this study is to test an eating disorders prevention digital chatbot program in a diverse group of adolescents.

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Key information

Age range

13 year–19 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Washington University in St. Louis

St Louis, Missouri, 63130, United States

Location status: Recruiting

Location contact

Ellen E Fitzsimmons-Craft, PhD

PRINCIPAL_INVESTIGATOR

Marianna Horton, B.S./B.A.

CONTACT

[email protected]

314-935-5843

Nathalie A Gullo, B.S./B.A.

CONTACT

[email protected]

314-935-5843

About this study

Eating disorders (EDs) are impacting youth at extreme rates, with up to 22% of adolescents reporting ED symptoms, and are associated with very high psychiatric comorbidity. Since adolescence is a critical period for the onset of eating disorders, prevention during this stage is essential to reducing lifetime prevalence. Interventions have been developed to prevent the onset of these devastating disorders, but these programs are generally not publicly available and rarely offer support for addressing comorbidity or the unique needs of vulnerable subpopulations (e.g., low-income populations, sexual and gender minorities, racial/ethnic minorities, those from rural areas), who are even less likely to have access to high-quality care. One scalable, engaging, easy-to use, and convenient approach to increasing access to evidence-based EDs prevention for underserved groups involves using a chatbot. This project will adapt our team's existing EDs prevention chatbot for use with adolescents, including those from diverse backgrounds, and evaluate its effectiveness. Our deep industry and non-profit partnerships will ensure scalability and ultimate real-world impact.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 13 - 19 years old
  • Owns a smartphone
  • Speaks English
  • US resident
  • Screens as at-risk for an eating disorder
  • Not currently in treatment for an eating disorder

Exclusion criteria

  • Below 13 or older than 19 years of age
  • Does not own a smartphone
  • Does not speak English
  • Lives outside the US
  • Screens as:
  • Having a subclinical or clinical ED
  • Not at risk for an ED
  • In treatment for an ED

Treatment and study plan

Wysa Digital Chatbot Program

Behavioral

Wysa is a digital rules-based chatbot program platform offering cognitive-behavioral therapy-based guided self-help modules, including five modules for eating and body image developed by our team. Participants in this arm will engage with the digital chatbot program daily for three months to complete all five modules.

Primary outcomes

  1. ED risk factors; Weight Concerns Scale

    Time frame: 6 - months

    Weight concerns scale as found in the Stanford Washington Eating Disorder (SWED) screen is a 5-item validated self-report questionnaire which measures concern with weight and dieting. Each item is scored on a 5-100 scale, then an average is computed across all 5 items for a 0-100 score.

Study contacts

Contact information is provided by the study sponsor or research team.

Marianna Mohr, B.S./B.A.

CONTACT

[email protected]

314-935-5843

Mireya De Los Reyes, B.S/B.A.

CONTACT

[email protected]

314-935-5843

Sponsors and collaborators

Lead sponsor

Washington University School of Medicine

Other

Registry information

Official study title

Improving Access to Services, Preventing Eating Disorders, and Addressing Comorbid Depression and Anxiety in Diverse Adolescents

Acronym: EMBody

Important dates

Study start
2024
Primary completion
2027
Study completion
2027
First posted
Jul 30, 2025
Registry last updated
Jul 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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