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Enrolling by Invitation

NCT Number: NCT07017075

Adjusting CPR Location With TEE Guidance

Use Transesophageal ultrasound in OHCA patients to identify the proper compression location

Enrolling by Invitation

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Chang Bing Show Chawan Memorial Hospital, Changhua, Taiwan

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About this study

For patients with cardiac arrest, high-quality cardiopulmonary resuscitation is performed according to critical care management and Advanced Cardiac Life Support (ACLS). Rapid with powerful chest compression should be performed to maintain the heart's output and blood flow. An advanced airway should be established and adjust resuscitation based on collected clinical information. Transesophageal ultrasound examination is performed after the advanced airway is established without affecting the resuscitation. The investigators use the built-in ultrasound software (Philips QLAB 3D quantification advance, Philips Healthcare, USA, speckle tracking echocardiography (STE,Speckle tracking echocardiography)) to analyze stroke volume and cardiac output. The investigators collect the stroke volume and cardiac output at the chest compression position recommended by ACLS, as well as the stroke volume and cardiac output after adjusting the optimal chest compression position. The investigators expect it can increase the return of spontaneous circulation rate, survival rate, and neurological prognosis over time.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Out-of-hospital cardiac arrest patients

Exclusion criteria

  • DNR was signed
  • Age under 18
  • Trauma patients
  • Patients hard to establish an advanced airway
  • Inavailability of ultrasound machine or operators

Treatment and study plan

adjustment of CPR location

Behavioral

Transesophageal ultrasound with built-in ultrasound software (Philips QLAB 3D quantification advance, Philips Healthcare, USA, speckle tracking echocardiography (STE,Speckle tracking echocardiography) to evaluate stroke volume and cardiac output in traditional CPR location and the better position

Primary outcomes

  1. stroke volume, ejection fraction, end-diastolic volume, and end-systolic volume

    Time frame: 2 mins

    built-in ultrasound software (Philips QLAB 3D quantification advance, Philips Healthcare, USA, speckle tracking echocardiography (STE,Speckle tracking echocardiography)

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Collaborators

  • Chang Bing Show Chwan Memorial Hospital

Registry information

Official study title

3D Visulization The Area Of Maximal Compression And Quantitative Assessment Stroke Volume And Ejection Fraction After Adjusting CPR Location

Important dates

Study start
2025
Primary completion
2026
Study completion
2027
First posted
Jun 12, 2025
Registry last updated
Nov 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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