Adjunctive Study of AL-37807 Ophthalmic Suspension

The purpose of the study is to compare the safety and intraocular pressure-lowering efficacy of AL-37807 ophthalmic suspension vs. Timolol gel forming solution vs. AL-37807 vehicle, all dosed concomitantly with Xalatan, in patients with open-angle glaucoma or ocular hypertension.

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Key information

Conditions

Open-angle Glaucoma Cardiovascular Diseases Eye Diseases Glaucoma Glaucoma, Open-Angle Hypertension Ocular Hypertension Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Contact Alcon Call Center at 1-888-451-3937

Fort Worth, Texas, 76134, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Open-angle glaucoma
Ocular hypertension
Must have been on Xalatan for at least 3 months
VA not worse than 0.60
Other protocol-defined inclusion criteria may apply

Exclusion criteria

Age related
Other protocol-defined exclusion criteria may apply

Treatment and study plan

AL-37807 ophthalmic suspension, 0.1%

Drug

Timolol gel forming solution, 0.5%

Drug

AL-37807 ophthalmic solution vehicle

Other

Latanoprost ophthalmic solution

Drug

Other names: XALATAN

Primary outcomes

Mean change from baseline in intraocular pressure

Time frame: Baseline, up to 4 weeks

Sponsors and collaborators

Lead sponsor

Alcon Research

Industry

Registry information

Official study title

Comparison of Safety and Efficacy of Al-37807 Ophthalmic Suspension vs. Timolol Gel Forming Solution and Vehicle, All Dosed Concomitantly With Xalatan in Patients With Open-Angle Glaucoma or Ocular Hypertension

Important dates

Study start: 2007
Primary completion: 2008
Study completion: 2008
First posted: Feb 21, 2008
Registry last updated: Dec 5, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed