Skip to main content
OpenTrials
Completed

NCT Number: NCT04399187

Adjunctive Local Sodium Hypochlorite Gel in Non Surgical Periodontal Debridement

The aim of this study was to assess the efficacy of minimally invasive nonsurgical debridement (MINSD) of periodontal pockets with or without local amino acid buffered sodium hypochlorite (NaOCl) gel application after 6 months follow-up.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Periodontal Diseases Mouth Diseases Stomatognathic Diseases

Age range

32 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Messina

Messina, 98100, Italy

About this study

Forty periodontal compromised patients were randomly allocated in two groups. Periodontal pockets > 5 mm in patients of test group were treated by MINSD and NaOCl gel application, meanwhile in patients of control group MINSD alone was performed. Full-mouth plaque score (FMPS) , Full-mouth bleeding score (FMBS), probing depth (PD), clinical attachment level (CAL) and gingival recession (GR) were assessed at baseline and after 6 months follow-up.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients diagnosed with periodontitis;
  • Age > 18 years old;
  • Patients with at least 10 teeth for arch;
  • Presence at least of two teeth with PD > 5 mm for quadrant;
  • Single-rooted and multi-rooted teeth;

Exclusion criteria

  • Patients with systemic diseases;
  • Pregnant or lactating;
  • Tobacco smokers (> 10 cigarettes/day);
  • Previous periodontal treatment in the last 2 years;
  • Prolonged antibiotic treatment or anti-inflammatory treatment within 6 months prior to periodontal therapy;
  • Furcation involvement;
  • Acute periodontal or endodontic abscess;
  • Third molars

Treatment and study plan

Sodium hypochlorite gel application

Drug

Patients treated by scaling and root planing and Sodium hypochlorite gel application, meanwhile in patients of control group scaling and root planing alone was performed.

Other names: Gel application

Primary outcomes

  1. Probing depth changes

    Time frame: 6-months

    Changes over time in probing depth millimiters

Sponsors and collaborators

Lead sponsor

University of Messina

Other

Registry information

Official study title

Clinical Effects of Adjunctive Local Sodium Hypochlorite Gel in Minimally Invasive Non Surgical Debridement (MINSD) of Periodontal Pockets. A 6-month Randomized Controlled Clinical Trial

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
May 22, 2020
Registry last updated
May 22, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.