Adherence of Stalevo, Entacapone and Levodopa

To test if combining two antiparkinson drugs into a single tablet improves accuracy of medicine intake by the patient.

To test if patients with Parkinson's disease who take medicines at regular time intervals have smoother symptom control.

Completed

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Key information

Conditions

Parkinson's Disease Basal Ganglia Diseases Brain Diseases Central Nervous System Diseases Movement Disorders Nervous System Diseases Neurodegenerative Diseases Parkinson Disease Parkinsonian Disorders Synucleinopathies

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Southern General Hospital

Glasgow, Scotland, G51 4TF, United Kingdom

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients diagnosed with Parkinson's disease aged between 18 and 85 years fulfilling UK Brain Bank criteria.
Current levodopa therapy prescribed on a regular basis three or more times per day but requiring entacapone because of 'wearing off'
Able to manipulate electronic monitoring bottles and complete questionnaires

Exclusion criteria

Current use of compliance aid such that study participation would be detrimental to patient's adherence
Pregnancy or breast feeding
Excess alcohol (over 21 units per week for women and 28 units for men)
Mini mental state examination of less than 26.
Severe depression (Geriatric depression score over 20)

Sponsors and collaborators

Lead sponsor

South Glasgow University Hospitals NHS Trust

Other

Registry information

Official study title

Study of Adherence of Stalevo, Entacapone and Levodopa

Important dates

Study start: 2005
Study completion: 2006
First posted: Oct 28, 2005
Registry last updated: May 23, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed