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NCT Number: NCT01449097

Adductor-Canal-Blockade Versus the Femoral Nerve Block Effect on Muscle Strength and Mobilization in Healthy Volunteers

The aim of this study is to investigate the efficacy of the Adductor-Canal-Blockade versus the femoral nerve block versus placebo on muscle strength in healthy volunteers. The investigators hypothesize that the Adductor-Canal-Blockade results in a lesser reduction of the quadriceps muscle strength compared to the femoral nerve block.

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Key information

Conditions

Muscle Strength Healthy Volunteers

Age range

18 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Phase 4

Primary location

Department of Anaesthesia, Centre of Head and Orthopaedics, Copenhagen University Hospital, Rigshospitalet

Copenhagen, 2100, Denmark

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • written informed consent
  • ASA 1
  • BMI > 18 og < 25

Exclusion criteria

  • Can not cooperate to the exam
  • Do not speak or understand Danish
  • Drug allergy
  • Alcohol or drug abuse
  • Daily consumption of analgetics on prescription
  • Any drug intake within the last 48 hours
  • Neuromuscular defects in the femoral nere, the obturator nerve or the muscles of the thigh.
  • Previous surgery or trauma to the lower limb
  • Diabetes Mellitus
  • Intake of steroids, except steroids for inhalation
  • Physical exercise within the last 24 hours prior to Day 1 and 2 of the study

Treatment and study plan

Adductor-Canal-Blockade

Procedure

US-guided Adductor-Canal-blockade with Ropivacaine

The femoral nerve block

Procedure

US-guided femoral nerve block with ropivacaine

Placebo

Procedure

US-guided Adductor-Canal-Blockade/femoral nerve block with saline

Primary outcomes

  1. the difference in quadriceps muscle strength between the Adductor-Canal-Blockade and placebo

    Time frame: 0-6 hours

Secondary outcomes

  1. The difference in quadriceps muscle strength between the Adductor-Canal-Blockade and the femoral nerve block

    Time frame: 0-6 hours

  2. The difference in quadriceps muscle strength between the placebo and the femoral nerve block

    Time frame: 0-6 hours

  3. The difference in adductor muscle strength between the groups

    Time frame: 0-6 hours

  4. The difference in mobilization between the groups

    Time frame: 0-6 hours

Sponsors and collaborators

Lead sponsor

Rigshospitalet, Denmark

Other

Registry information

Official study title

Comparison of the Efficacy of the Adductor-Canal-Blockade Versus the Femoral Nerve Block on Muscle Strength and Mobilization in Healthy Volunteers: a Randomized Study

Important dates

Study start
2011
Primary completion
2011
Study completion
2011
First posted
Oct 7, 2011
Registry last updated
Dec 22, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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