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OpenTrials
Completed

NCT Number: NCT00628979

Addressing Help-Seeking Barriers in Developing an Intensive Treatment for Veterans With Panic Disorder

The purpose of this study is to understand some of the reasons why recently deployed veterans decline psychosocial treatment options for panic disorder and to test a brief weekend treatment for panic attacks.

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Key information

Age range

18 year–74 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Michael E. DeBakey VA Medical Center (152)

Houston, Texas, 77030, United States

About this study

The population of interest for this program includes men and women returning from deployment in Iraq or Afghanistan who are seen in the TRP at the MEDVAMC. The study consists of two parts: PART 1 involves a qualitative investigation of treatment-seeking barriers specific to persons who refuse standard treatments and PART 2 is a pilot intervention to treat panic symptoms in service members who have co-existing PTSD symptoms. PART 1 will include approximately 15 individuals who will be interviewed by a member of the study staff. Patients will be interviewed individually following a semi-structured questionnaire designed to help identify treatment-seeking barriers. PART 2 will include 8 individuals who will be enrolled in an open-trial of a two-day intensive cognitive-behavioral treatment for panic disorder, which will occur over the weekend. No participants will be assigned to a control condition. All activities related to this project including the interviews and intervention will be delivered in either the TRP at the MEDVAMC or at the Houston Center for Quality of Care and Utilization Studies (HCQCUS), a nearby facility.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Veterans;
  • age 18-74;
  • current diagnosis of panic disorder;
  • PTSD symptoms that either meet full diagnostic criteria from the Diagnostic and Statistical Manual-Fourth Edition (DSM-IV) or are at a sub-clinical level. Sub-clinical PTSD is defined as patients who meet either PTSD criteria B and C or B and D, but fail to meet all three;
  • panic disorder and PTSD present for at least 1 month;
  • PART 1 only: patients who are clinically eligible to participate in the study and refuse standard psychosocial treatments (e.g., 12 weeks of cognitive behavioral therapy) for panic disorder.

Exclusion criteria

  • Current substance dependence;
  • diagnosed with bipolar disorder or psychosis;
  • current suicidal/homicidal ideation and intent;
  • severe depression (precluding participation in a research study);
  • panic attacks related only to a diagnosis of a specific phobia;
  • medical conditions mimicing anxiety (e.g., mitral valve prolapse);
  • PART 1 only: patients who are clinically eligible for the study and are willing to engage in a minimum of 12 weeks of psychosocial treatment for panic disorder.

Treatment and study plan

CBT

Behavioral

cognitive- behavioral treatment for panic disorder.

Primary outcomes

  1. Qualitative data regarding treatment seeking barriers

    Time frame: 6 months

Secondary outcomes

  1. Panic attack frequency and severity; treatment acceptability

    Time frame: 6 months

Sponsors and collaborators

Lead sponsor

US Department of Veterans Affairs

Fed

Registry information

Important dates

Study start
2008
Primary completion
2008
Study completion
2009
First posted
Mar 5, 2008
Registry last updated
Jul 3, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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