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NCT Number: NCT07599241

Additive Efficacy of Physical Activity Program in Hypthyroidism Elder Females With Glaucoma and Fatty Liver Issues

additive efficacy of physical activity program in hypthyroidism in elder females with glaucoma and fatty liver issues was not investigated

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Key information

Age range

65 year–75 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Cairo University

Dokki, Giza Governorate, 11432, Egypt

Location status: Recruiting

Location contact

ali AM Ismail, lecturer

CONTACT

[email protected]

+201005154209

About this study

hypthyroidism elder females (n=40) with glaucoma and fatty liver issues will randomly divided into group number 1 (n=20) that will recive their levothyroxine and physical activity program on treadmill thrice weehly for 6 month or group number II (n=20) that will receive levothyroxine only

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • subclinical hypothrodism (significant form)
  • primary opened angle gaulcoma in both eyes with ocular hypertension in both eyes )(high-tension typed glaucoma)
  • fatty liver (non alcholic type)
  • elder females

Exclusion criteria

  • respiratory issues
  • cardiac issues
  • renal issues

Treatment and study plan

Physical activity

Behavioral

hypthyroidism elder females (n=20) with glaucoma and fatty liver issues that will recive their levothyroxine and physical activity program on treadmill thrice weehly for 6 month

Usual Care

Other

hypthyroidism elder females (n=20) with glaucoma and fatty liver issues that will recive their levothyroxine only

Primary outcomes

  1. intraocular pressure

    Time frame: 6 months

    it will be assessed in both eyes

Secondary outcomes

  1. body mass index

    Time frame: 6 months

    it will be assessed on empty stomach and bladder

  2. waist circumfrence

    Time frame: 6 months

    it will be assessed by tape at umblical level

  3. systolic blood pressure

    Time frame: 6 months

    it will be assessed by sphygmomanmometer

  4. diastolic blood pressure

    Time frame: 6 months

    it will be assessed by sphygmomanmometer

  5. glaucoma assocaited life quality survey

    Time frame: 6 months

    it is a questionaire evaluates life quality

  6. triglyceridss

    Time frame: 6 months

    it will be assessed in serum

  7. high density lipoproteines

    Time frame: 6 months

    it will be assesed in serum

  8. alanine transamianses

    Time frame: 6 months

    it will be assessed in serum

  9. aspartate trasnamiansses

    Time frame: 6 months

    it will be assessed in serum

  10. physical conclusion of short form survey

    Time frame: 6 months

    it will assess physical quality of lifes of females

  11. Mental conclusion of short form survey

    Time frame: 6 months

    it will assess physical quality of lifes of females

  12. thyroid stimualting horomone

    Time frame: 6 months

    it will be assessed in serum

  13. fasting glycemia value

    Time frame: 6 months

    it will be assessed in serum

Study contacts

Contact information is provided by the study sponsor or research team.

Ali MA Ismail, lecturer

CONTACT

[email protected]

01005154209

fatma M Ali

CONTACT

[email protected]

01031321109

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
May 20, 2026
Registry last updated
May 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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