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Completed

NCT Number: NCT01656707

Adaptive Treatment for Adolescent Cannabis Use Disorders

The purpose of this study is to examine an Adaptive Treatment approach in order to improve outcomes of youth with Cannabis Use Disorders who are poor responders to treatment.

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Key information

Age range

13 year–18 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Connecticut Health Center

Farmington, Connecticut, 06030-2103, United States

About this study

The study will address the current contrasts in youth response to treatment, the problem of poor response to treatment and the prevention of relapse. Results from the study may support Adaptive Treatment as an efficacious approach for youth with Cannabis Use Disorder who are poor responders to treatment.

Poor responders fall into two categories, those who failed to achieve a negative drug urinalysis during the last session of the initial MET/CBT-7 treatment they attended, and those who either dropped out or were administratively discharged at any time during the initial MET/CBT-7 treatment.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 13-18 years of age at the time of intake assessment
  • Current diagnosis of DSM-IV Cannabis Abuse or Dependence
  • Able to read and comprehend English at a 5th grade level
  • Residence within 45 minutes drive from the UCHC Farmington treatment site
  • Participant and a parent/legal guardian responsible for providing collateral information agree to sign an IRB approved consent form
  • Participant and a parent/legal guardian responsible for providing collateral information agree to provide locator information
  • The family is not planning to move from the area during the next six months

Exclusion criteria

  • Meet criteria for dependence of any other substance of abuse other than nicotine or alcohol
  • Report suicidal ideation with a plan, suicidal behavior, a plan to hurt oneself or other, or a history of self-injurious behavior all occurring in the last 30 days
  • Meet a lifetime diagnosis of schizophrenia
  • Has any current health (i.e. medical, psychiatric) condition that will compromise the participant's ability to regularly attend treatment
  • Demonstrate an inability or unwillingness to provide locator information

Treatment and study plan

ACRA

Behavioral

Ten weekly,60-minute therapy sessions including six individual, two parent/guardian and two joint (individual and parent/guardian).

Other names: Adolescent Community Reinforcement Approach

CBT

Behavioral

10 weekly, 60-minute sessions of augmented individualized CBT

Other names: Cogntive Behavioral Therapy

Primary outcomes

  1. 1.) To evaluate the efficacy of AT for youth who have been defined as poor responders to an evidence-based practice intervention such as the initial MET/CBT-7.

    Time frame: one year

    Each participant will serve as his/her own control. The outcomes will include the T-ASI, T-ASI-P, and drug urinalyses.

Secondary outcomes

  1. To assess outcomes as a function of mediator variables such as self-efficacy, coping skills, readiness to change, and environmental support (i.e., family and peer), within each of the AT interventions.

    Time frame: one year

    The secondary outcome measures will include the SCQ, CRI, PRQ, and SSQ.

Sponsors and collaborators

Lead sponsor

UConn Health

Other

Collaborators

  • National Institute on Drug Abuse (NIDA)

Registry information

Important dates

Study start
2011
Primary completion
2016
Study completion
2016
First posted
Aug 3, 2012
Registry last updated
Apr 11, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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