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OpenTrials
Completed

NCT Number: NCT02205710

Adaptive Cognitive Training in Healthy Older Adults

Cognitive training has emerged as a promising method to maintain, enhance, and rehabilitate cognitive function in older adults and individuals with dementia. In recent years, such training has become particularly appealing in the clinical context, with many paradigms aimed specifically at adults experiencing various stages of cognitive decline due to Mild Cognitive Impairment, Alzheimer's disease, and vascular dementias. However, basic questions remain. For example, uncertainty persists regarding factors that influence observed improvements as well as the conditions that would maximize transfer and sustainability of training effects. The objective of this study is to evaluate factors that may maximize the benefits of computerized cognitive training in older adults.

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Key information

Conditions

Mild Cognitive Impairment Alzheimer Disease Alzheimer's Disease Brain Diseases Central Nervous System Diseases Cognition Disorders Cognitive Dysfunction Dementia Mental Disorders Mild to Moderate Dementia Nervous System Diseases Neurocognitive Disorders Neurodegenerative Diseases Tauopathies

Age range

60 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Bruyere Continuing Care

Ottawa, Ontario, K1N 5C8, Canada

About this study

The study involves 25 sessions of an adaptive cognitive training program, completed over 5 weeks. Pre and post training assessments will evaluate any near and far transfer effects of training.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • English as the maternal or primary spoken language.
  • Good self-reported health (i.e., no cerebro-, or cardio-vascular disease or neurological disease).
  • Normal or corrected-to-normal vision and hearing.

Exclusion criteria

  • Poor hearing or vision
  • Inadequate understanding of the English language

Treatment and study plan

Computerized cognitive training

Other

Other names: Activate

Computerized games

Other

Primary outcomes

  1. Change in ratings on cognitive training survey

    Time frame: Baseline, week 5

    This survey aims to assess participant perceptions on cognitive training, and includes a series of related questions, rated on a scale of 1-7.

  2. Change in neural activity

    Time frame: Baseline, week 5

    We will measure resting state as well as task-related EEG responses to determine the effects of cognitive training at the neural level.

  3. Change in performance on neuropsychological tests

    Time frame: Baseline, week 5

    Using a set of standard neuropsychological evaluations, we will measure changes in attention, memory, and executive function following cognitive training.

Secondary outcomes

  1. Change in ratings of psychological wellbeing

    Time frame: Baseline, week 5

    We will use standardized questionnaires to assess quality of life, in order to measure the influence of cognitive training on factors related to wellbeing.

Sponsors and collaborators

Lead sponsor

Bruyère Health Research Institute.

Other

Collaborators

  • University of Ottawa

Registry information

Important dates

Study start
2016
Primary completion
2018
Study completion
2018
First posted
Jul 31, 2014
Registry last updated
Aug 2, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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