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NCT Number: NCT07064824

Adaptive Cell Phone Support (ACPS)

The goal of this pilot clinical trial is to test a mobile health intervention for promoting medication adherence in a population of adolescents and young adults with chronic health conditions. The main question it aims to answer is:

-Is an adaptive intervention (personalizing the intensity of support based on patients' needs) efficacious for promoting medication adherence Researchers will compare the adaptive intervention to automated text message reminders see if the adaptive intervention shows stronger positive effects on medication adherence.

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Key information

Age range

15 year–20 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Children Hospital Los Angeles

Los Angeles, California, 90027, United States

Location contact

Caitlin Sayegh, PhD

CONTACT

[email protected]

13233617748

Caitlin Sayegh, PhD

PRINCIPAL_INVESTIGATOR

About this study

Plan to enroll 96 participants in this study, which is a sequential randomized trial.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children's Hospital Los Angeles patient
  • between 15-20 years old
  • taking at least one oral medication per day for a chronic health condition
  • English speaking
  • demonstrating sufficient cognitive capacity to engage in the assent/consent process and study procedures

There is no exclusion criteria.

Treatment and study plan

Adaptive Cell Phone Support

Behavioral

Mobile health adherence promotion based on the supportive accountability model

Computer-Delivered Cell Phone Support

Behavioral

Mobile health adherence promotion based on the supportive accountability model

Automated Text Reminders

Behavioral

Scheduled text reminder to take medication

Primary outcomes

  1. Mean scores on the Mobile Health App Usability Questionnaire

    Time frame: Baseline to 12 weeks

    Higher scores indicate greater ease with which users can use technology to achieve a particular goal; the minimum value of this questionnaire is 1 and the maximum value is 7.

  2. Total scores on the theoretical framework of acceptability questionnaire

    Time frame: Baseline to 12 weeks

    Higher scores indicate a greater "extent to which people delivering or receiving a healthcare intervention consider it to be appropriate, based on anticipated or experienced cognitive and emotional responses to the intervention"; the minimum value of this questionnaire is 7 and the maximum value is 35.

  3. Total scores on the Visual Analogue Scale

    Time frame: Baseline to 12 weeks

    Percentage of doses taken our of 100%; higher numbers indicate greater medication adherence. This scale presents participants with a line, marked 0 on the left and 100 on the right, and participants can drag a marker to the place on the line that best visually indicated their adherence.

  4. Total scores on Rollnick's Readiness Ruler

    Time frame: Baseline to 12 weeks

    Higher scores on this measure indicate more motivation to take medication as prescribed; the minimum value of this questionnaire is 0 and the maximum value is 10.

  5. Total Transition Readiness scores on the Successful Transition to Adulthood with Therapeutic = Rx Questionnaire

    Time frame: Baseline to 12 weeks

    Higher scores on extent to which patients are prepared to manage their health condition as adults, outside of the pediatric system; ; the minimum value of this questionnaire is 0 and the maximum value is 90.

Study contacts

Contact information is provided by the study sponsor or research team.

Caitlin Sayegh, PhD

CONTACT

[email protected]

13233617748

Sponsors and collaborators

Lead sponsor

Children's Hospital Los Angeles

Other

Registry information

Official study title

Adaptive Cell Phone Support to Promote Medication Adherence Among Adolescents and Young Adults With Chronic Health Conditions

Acronym: ACPS

Important dates

Study start
2027
Primary completion
2029
Study completion
2030
First posted
Jul 15, 2025
Registry last updated
Jul 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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