Mass General Brigham Cancer Institute at Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
Location status: Recruiting
Recruiting
NCT Number: NCT07139769
Adapting Psychosocial Resiliency Intervention for Parents of Adolescents and Young Adults With Cancer
The study team aims to adapt a psychosocial intervention to reduce psychological distress among the caregiving parents of adolescents and young adults (aged 15-39) who have cancer. First, the study team will adapt an evidence-supported, group-based program for improving psychological resiliency (Stress Management and Resiliency Training - Relaxation Response Resiliency Program; SMART-3RP(E. R. Park et al., 2021)), and iteratively incorporate feedback from parents of AYA with cancer using a mixed-methods approach. Next, the study team will pilot the refined intervention to assess for preliminary indicators of feasibility, acceptability, and potential for efficacy in reducing parental distress.
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
18 year and older
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Self-identifying parent/guardian who provides a primary informal caregiving role in their child's cancer
- Recipient of caregiving is aged between 15 and 39 years and is receiving treatment for cancer
- Participant must score equal to or greater than 2 (out of a possible 10) on the National Comprehensive Cancer Network Distress Thermometer
- English-speaking
- Aged over 18 years
Exclusion criteria
- Having a co-parent or other household member participating in the same study
- Active symptoms of psychosis or suicidal ideation that would preclude safe participation
Treatment and study plan
Psychosocial Intervention for Parental Caregivers of AYA with Cancer
BehavioralA new adaptation of an evidence-supported intervention, the SMART-3RP program, to address psychological symptoms and promote well-being among parental caregivers of AYA with cancer.
Primary outcomes
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Intervention Feasibility: Percent of Identified Prospective Participants Who Enroll
Time frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Percent of eligible participants who were offered participation and who enroll in the study by completing consent and baseline assessment.
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Intervention Feasibility: Proportion of Participants Completing the Program
Time frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Percent of enrolled participants who complete the program, defined as completing 6 out of 8 sessions.
-
Intervention Acceptability
Time frame: Post-treatment completion (enrollment to treatment completion is approximately 3 months)
Acceptability will be assessed by the Client Satisfaction Questionnaire (CSQ-8). The intervention study will be considered acceptable if ≥80% of participants rate it as acceptable (defined as a CSQ-8 score ≥20).
Study contacts
Contact information is provided by the study sponsor or research team.
Xinghan Zhu, B.S.
CONTACT
Zeba N Ahmad, Ph.D.
CONTACT
Sponsors and collaborators
Lead sponsor
Zeba Ahmad, Ph.D.
Other
Collaborators
- American Cancer Society, Inc.
Registry information
Official study title
The RAISE Study: Adapting Psychosocial Resiliency Intervention for Parents of Adolescents and Young Adults With Cancer
Acronym: RAISE
Important dates
- Study start
- 2025
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Aug 24, 2025
- Registry last updated
- Dec 5, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.