Nuffield Laboratory of Ophthalmology
Oxford, OX3 9DU, United Kingdom
NCT Number: NCT02729818
Microperimetry is a relatively new and extremely sensitive method of assessing visual function. It projects light stimuli onto a defined area of the retina to map retinal perceptual thresholds. Participants look at a focal point and press a button to indicate when they have seen a light stimulus. The stimuli vary in intensity to find the participant's visual sensitivity.
Microperimetry is carried out in low light conditions. Before testing, participants must adapt to the low light conditions in a process called 'dark adaptation.' Currently there is no consensus on the optimal time needed for dark adaptation. Investigators know that visual sensitivity differs in differing light conditions. Failing to sufficiently dark-adapt may therefore adversely affect test results.
The aim of this study is to establish the optimal length of dark adaptation for microperimetry performance in healthy volunteers. On day 1, participants will undergo training field tests to reduce a learning effect affecting the results. Tests will then be performed following 5 mins adaptation, 10 mins adaptation and 30mins adaptation, On day 2, participants will perform testing following no adaptation time, 15 mins adaptation, and 20 mins adaptation. Statistics will be used to determine the effect of adaptation time on average threshold measures.
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Notify Me18 year and older
All sexes
Observational
Oxford, OX3 9DU, United Kingdom
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: Different time intervals for adaptation prior to testing; 0 minutes, 5, 10, 15, 20 and 30 minutes on day 1 and day 2.
The average threshold for each test is detailed on the microperimetry printout and is measured in dB. This will be measured by testing following each time interval specified.
Time frame: Different time intervals for adaptation prior to testing; 0 minutes, 5, 10, 15, 20 and 30 minutes on day 1 and day 2
The fixation stability for each test is detailed on the microperimetry printout and is measured in degrees for the area covering 95% of the fixation points. This will be measured by testing following each time interval specified.
University of Oxford
Other
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