MUSC
Charleston, South Carolina, 29425, United States
Completed
NCT Number: NCT01852227
ADAPT A Direct Aspiration, First Pass Technique for the Endovascular Treatment of Stroke
In collaboration with the Neurointerventional programs at state university of new york Buffalo, state university of new york Stonybrook, Swedish Medical Center, Erlanger Health System, Vanderbilt University, and West Virginia University School of Medicine, the investigators aim to prospectively collect experiences where direct aspiration as a first pass technique is used for thrombectomy procedures.
The investigators also want to compare specific characteristics from these cases to other stroke cases where traditional thrombectomy devices were used.
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About this study
Traditionally, at a physician's discretion, first pass attempts at thrombectomy procedures are performed with any number of FDA cleared catheters, guide wires, and devices designed for efficient removal of clot within an intracranial vessel. Among institutions involved in this case study, the latest devices are readily available and fully support standard treatment paradigms.
However, several cases, recently completed, using only large bore catheter and aspiration have anecdotally demonstrated a superior ability to remove clot from vessels, restoring blood flow to the affected vessel and brain tissue. In these limited number of cases, full restoration of blood flow has been achieved. While this combination of approved devices is minimalistic, the efficiency of the procedure, rapid technical success, and relative simplicity of the approach is unique and should be thoroughly reviewed and possibly prepared for publication.
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- All patients who were treated with direct aspiration as a first pass choice or treated with a stent retriever will be included.
Exclusion criteria
- Patients not treated with either direct aspiration as a first pass, or stent retriever will not be included.
Treatment and study plan
Primary outcomes
-
Discharge national institutes of health stroke scale (NIHSS)
Time frame: approximately 7 days after index stroke
a national institutes of health stroke scale (NIHSS) will be obtained at the time of the each patient's discharge or approximately 7 days
Secondary outcomes
-
90 day modified Rankin Score (mRS)
Time frame: 90 days after procedure
90 days after procedure each patient's modified Rankin Score will be obtained.
Sponsors and collaborators
Lead sponsor
Medical University of South Carolina
Other
Collaborators
- State University of New York - Downstate Medical Center
- Stony Brook University
- Swedish Medical Center
- Vanderbilt University
- West Virginia University
Registry information
Important dates
- Study start
- 2013
- Primary completion
- 2014
- Study completion
- 2016
- First posted
- May 13, 2013
- Registry last updated
- Oct 3, 2017
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.