Skip to main content
OpenTrials
Active, Not Recruiting

NCT Number: NCT06281054

Acute Myocardial Infarction in Cancer Patients

Using national health insurance service database, current study aim to evaluate the risk and prognosis of acute myocardial infarction in cancer patients and to find the optimal treatment strategy for acute myocardial infarction that can improve long-term prognosis.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Acute Myocardial Infarction Cancer Neoplasms

Sex eligibility

All sexes

Study type

Observational

Primary location

Chonnam National University Hospital, Chonnam National University Medical School

Gwangju, South Korea

About this study

This study will be conducted using Korean National Health Insurance Service database. Patients who were diagnosed with cancer from 2002 to 2021 will be included in the study. Using the selected patients, current study will analyze the incidence and prognosis of acute myocardial infarction in cancer patients and the prognosis according to the treatment method for acute myocardial infarction will be compared. Primary outcome will be all-cause death. Secondary outcomes will be myocardial infarction, revascularization, hospitalization for heart failure, stroke, and clinically relevant bleeding.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients diagnosed with cancer between 2002 and 2021
  • Patients who were diagnosed with acute myocardial infarction after cancer diagnosis

Exclusion criteria

  • Patients who died during period of cancer diagnosis

Treatment and study plan

Revascularization

Procedure

Performing PCI or CABG

Primary outcomes

  1. All-cause death

    Time frame: 2-years after diagnosis of acute myocardial infarction

    All-cause death which was obtained from death certification collected by Statistics Korea at the Ministry of Strategy and Finance of South Korea

Secondary outcomes

  1. Myocardial infarction

    Time frame: 2-years after diagnosis of acute myocardial infarction

    Myocardial infarction is defined as presence of the diagnostic codes (ICD-10 I21, I22) in the primary position during hospitalization

  2. Revascularization

    Time frame: 2-years after diagnosis of acute myocardial infarction

    Percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG)

  3. Hospitalization for heart failure

    Time frame: 2-years after diagnosis of acute myocardial infarction

    Heart failure events requiring hospitalization defined as presence of the diagnostic codes (I110, I130, I132, I255, I420, I425-I429, I43, I50, I971) in the primary position during hospitalization

  4. Stroke

    Time frame: 2-years after diagnosis of acute myocardial infarction

    Stroke is defined as ischemic stroke (ICD-10 I63, I64) or intracranial hemorrhage (ICD-10 I60-62), combined with the codes of diagnostic brain imaging.

  5. Clinically relevant bleeding

    Time frame: 2-years after diagnosis of acute myocardial infarction

    Bleeding requiring hospitalization or transfusion

Sponsors and collaborators

Lead sponsor

Samsung Medical Center

Other

Collaborators

  • Chonnam National University

Registry information

Official study title

Risk and Clinical Outcomes of Acute Myocardial Infarction in Patients With Cancer: A Nationwide Study

Important dates

Study start
2002
Primary completion
2021
Study completion
2025
First posted
Feb 28, 2024
Registry last updated
Mar 14, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.