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OpenTrials
Completed

NCT Number: NCT04082312

Acute Kidney Injury in Adult Patients Supported by VA-ECMO

Post-cardiotomy cardiogenic shock (PCCS) occurs in 2-6% of patients undergoing cardiac surgery, and 1% of cardiac surgery patients will require mechanical circulatory support using Veno-Arterial ExtraCorporeal Membrane Oxygenation (VA-ECMO). Acute Kidney Injury is a frequent complication in this population and negatively impacts the survival. We aimed to determine whether the timing of ECMO implantation influence the renal prognosis of these patients.

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Key information

Conditions

Acute Kidney Injury Cardiogenic Shock Cardiovascular Diseases Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Heart Diseases Infarction Ischemia Kidney Diseases Male Urogenital Diseases Myocardial Infarction Myocardial Ischemia Necrosis Pathologic Processes Pathological Conditions, Signs and Symptoms Renal Insufficiency Shock Shock, Cardiogenic Urogenital Diseases Urologic Diseases Vascular Diseases

Age range

18 year–99 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Dr Adrien Bouglé

Paris, 75013, France

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients admitted in post-operative of cardiac surgery
  • Assisted by VA-ECMO

Exclusion criteria

  • Chronic hemodialysis
  • Death occurring within the first 48 hours of VA-ECMO implantation
  • Multiple VA-ECMO during the same hospitalization.

Treatment and study plan

No intervention

Other

No intervention

Primary outcomes

  1. Occurrence of a stage 3 AKI

    Time frame: Day 10 after ECMO implantation

    Number of Participants with Stage 3 Acute Kidney Injury according to the Kidney Disease: Improving Global Outcomes (KDIGO) group

Secondary outcomes

  1. Mortality at Day 30

    Time frame: Day 30 after ECMO implantation

    Number of Deceased Participants

  2. Mortality at 6 months

    Time frame: 6 months after ECMO implantation

    Number of Deceased Participants

Sponsors and collaborators

Lead sponsor

Groupe Hospitalier Pitie-Salpetriere

Other

Registry information

Official study title

Risk Factors and Prognosis of Acute Kidney Injury in Peri Operative Cardiac Surgery Adult Patients Supported by VA-ECMO

Acronym: AKI-ECMO

Important dates

Study start
2016
Primary completion
2019
Study completion
2019
First posted
Sep 9, 2019
Registry last updated
Sep 13, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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