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NCT Number: NCT07721220

Acute Effects of Neurodynamics on Strength and Endurance in Athletes

This study explores the acute effects of neurodynamics, an intervention commonly used by physical therapist to improve nerve mobility and decrease pain, on the strength and muscular endurance in the athletic population. This study aims to find if these interventions can maintain or promote strength and endurance in the hamstrings. The studies results will help physical therapist better prescribe exercise and hands-on treatment for hamstring and sciatic nerve related conditions and injuries.

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Key information

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

High Point University

High Point, North Carolina, 27268, United States

Location status: Recruiting

Location contact

Dr. Tommy Wyatt, DPT

CONTACT

[email protected]

856-381-6652

Tommy Wyatt, DPT

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants must be between 18 and 30 years of age.
  • Must be able to read, understand, and provide informed consent, in English.
  • Must be currently participating in an organized sport (e.g. collegiate, club, or competitive recreational level) or engaging in structured resistance training and athletic conditioning for recreational sports events (e.g 5k, marathon, Crossfit, Hyrox, etc).
  • Medically stable with no known contraindications to physical exertion.
  • Cleared for participation in strength or maximal-effort isometric testing.
  • Be able to perform lower extremity isometric testing without pain that limits maximal effort.
  • Must have 2 lower extremities capable to producing full range knee flexion and extension range of motion.
  • No medical condition that significantly alters lower extremity neuromuscular performance.
  • No history of lower extremity surgery in the past 12 months.

Exclusion criteria

  • Individuals younger than 18 or older than 30.
  • Acute lower extremity injury in the last 12 weeks.
  • Lower extremity surgery within the last 12 months.
  • Pain in either lower extremity that would limit maximal physical exertion.
  • History of neurological disorders, including but not limited to: Neuropathy, Stoke, MS, Parkinson's Disease, etc.
  • Use of medications that significantly impact neuromuscular performance, strength or fatigue.
  • No supplementation that affects neuromuscular performance, strength, or fatigue.
  • Unable to read and understand English.
  • Not in a vulnerable population: Pregnant, mentally or physically challenged, cognitively impaired.

Treatment and study plan

Sciatic Slider

Other

Mobility of a nerve, by placing tension on one end of the nerve and slacking (removing) tension off the other side of the nerve, through a full range of motion.

Sciatic Tensioner

Other

Loading the nerve, by placing tension on both ends of the nerve, isometrically at end range of motion.

Mechanically loaded neurodynamic sciatic floss

Other

Placing tension on one end of the nerve while taking the tension off the other end, under external load of an elastic resistance band.

Elastic Resistance Band

Device

Elastic resistance band was used to provide submaximal resistance during the mechanically loaded neurodynamic intervention.

Primary outcomes

  1. Isometric Strength

    Time frame: From initial strength and endurance test, to the post intervention strength and endurance test, assessed during a single study visit, assessed up to 30 minutes.

    Isometric strength of the hamstrings in knee flexion.

Secondary outcomes

  1. Endurance Ratio (isokinetic)

    Time frame: From initial endurance test to post intervention endurance test, during a single study visit, assessed up to 30 minutes.

    Endurance ratio of knee flexion, measured isokinetically.

Study contacts

Contact information is provided by the study sponsor or research team.

Dr. Tommy Wyat, DPT

CONTACT

[email protected]

856-381-6652

Sponsors and collaborators

Lead sponsor

High Point University

Other

Registry information

Official study title

Acute Effects of Neurodynamics on Strength and Endurance in Athletes: A Randomized Control Trial

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jul 22, 2026
Registry last updated
Jul 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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