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Completed

NCT Number: NCT06300294

Acute Coronary Syndrome and Acupressure

This study aims to examine the effect of acupressure on physiological parameters and anxiety levels in individuals diagnosed with Acute Coronary Syndrome (ACS).

H1-1: Acupressure applied to individuals with ACS has an effect on blood pressure.

H1-2: Acupressure applied to individuals with ACS has an effect on heart rate. H1-3: Acupressure applied to individuals with ACS has an effect on respiratory rate.

H1-4: Acupressure applied to individuals with ACS has an effect on pain levels. H1-5: Acupressure applied to individuals with ACS has an effect on anxiety levels.

H1-6: Acupressure applied to individuals with ACS has an effect on cortisol levels.

H1-7: Acupressure applied to individuals with ACS has an effect on ECG changes.

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Key information

Conditions

Acute Coronary Syndrome Anxiety Disorders Cardiovascular Diseases Heart Diseases Mental Disorders Myocardial Ischemia Nursing Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Manisa City Hospital

Manisa, 45000, Turkey (Türkiye)

About this study

Acute Coronary Syndrome (ACS) affects millions of people every year; It refers to three types of coronary artery disease: unstable angina pectoris, non-ST-elevation myocardial infarction (NSTE MI) and ST-elevation myocardial infarction (STEMI). It is known that 19 million people in the world and 161 thousand people in our country lost their lives due to Cardiovascular Disease (CVD). Approximately 3 million people worldwide die due to STEMI.Individuals experiencing ACS generally; It is observed that he/she experiences burning, stinging and compressive chest pain, tachycardia, sweating, fatigue, dizziness, dyspnea, nausea, anxiety and depression.Management of the disease is combined with pharmacological applications; It is tried to be provided with non-pharmacological applications such as education, acupuncture and acupressure. When the literature is examined, acupressure application; in the physiological parameters of individuals with myocardial infarction; It brings blood pressure, heart rate and respiratory rate to normal limits, and increases oxygen saturation and sleep quality; It appears to reduce anxiety and pain.For all these reasons, this study aims to examine the effect of acupressure on physiological parameters (blood pressure, heart rate, respiratory rate, pain and cortisol) and anxiety levels in individuals diagnosed with ACS.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Volunteer to participate in the study,
  • Those aged 18 and over
  • Able to speak Turkish
  • Diagnosed with ACS for the first time
  • Cardiopulmonary resuscitation not applied
  • No orientation problems (those who score 15 on the Glasgow Coma Scale)
  • Not diagnosed with psychiatric disease
  • No amputation, fistula, lymphedema, neuropathy or hemiplegia in any of the Upper Extremities
  • Those who underwent femoral intervention for CAG procedure
  • Those who have not used any integrative practices based on pressure and stimulation such as acupressure, acupuncture and reflexology in the last month.
  • Vital signs (28) are within normal range:

Blood pressure: 90/60-120/80 mmHg Heart rate: 60-100 min Respiratory rate: 12-18 min

Exclusion criteria

  • Those with arrhythmia (AF, VT etc.)
  • Patients who have previously undergone Coronary Angiography
  • Diagnosed with myocarditis, pericarditis
  • Those who do not take any speed-breaking drugs (beloc, arlec, etc.).
  • Patients who underwent radial intervention for CAG procedure

Treatment and study plan

Acupressure

Other
  • First follow-up (first 0-30 minutes of admission): Participants received routine care and treatment within the first 0-30 minutes of admission, in accordance with hospital protocol.
  • Second follow-up (6 hours after the CAG procedure): After the coronary angiography procedure was completed (after the sandbag was removed), the first acupressure application was performed on individuals whose vital signs were within the normal range.
  • Third follow-up (12 hours after the CAG procedure): Approximately 12 hours after the coronary angiography procedure, the second acupressure application was performed on individuals.
  • Fourth follow-up (Cortisol measurement): The fourth follow-up was conducted at 8:00 a.m. (sunrise) to determine cortisol levels. Physiological parameters were evaluated, and a venous blood sample was taken to determine cortisol levels.

Primary outcomes

  1. means of blood pressure

    Time frame: up to 30 minutes

    In this study, blood pressure was measured using monitors in the intensive care unit.

  2. means of hear rate

    Time frame: up to 30 minutes

    Heart rate is the pressure exerted on the vessel wall by the blood thrown by the left ventricle from the skin surface to the aorta during systole. In the research, heart rate is measured using a monitor.

  3. means of respiratory rate

    Time frame: up to 30 minutes

    Respiratory rate is the patient's breaths per minute. In this study, respiratory rate was taken from the monitor.

  4. means of cortisol.

    Time frame: up to 60 minutes

    The cortisol value in the blood will be measured.

Secondary outcomes

  1. means of subjective anxiety scores.

    Time frame: up to 30 minutes

    numerical anxiety scale. The total score between 0-10 obtained.

  2. means of subjective pain scores.

    Time frame: up to 30 minutes

    visual analog scale. It consists of a straight line with endpoints that define end limits such as "no pain" and "pain as bad as possible". The patient is asked to mark the level of pain on the line between the two endpoints.

  3. electrocardiography evaluation

    Time frame: up to 30 minutes

    Electrocardiography is the process of recording the electrical activity occurring in the heart to examine the functioning of the heart muscle and neural conduction system.

Sponsors and collaborators

Lead sponsor

Abant Izzet Baysal University

Other

Registry information

Official study title

The Effect of Acupressure on Anxiety And Physiological Parameters in Individuals Diagnosed With Acute Coronary Syndrome: A Randomized Controlled Study

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Mar 8, 2024
Registry last updated
May 26, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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