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OpenTrials
Completed

NCT Number: NCT02357641

Acute Coronary Disease (ACS)- Strain

Examination of probable distinction between cardiac or non- cardiac thoracal disorder via echocardiographic myocardial strain analysis

Completed

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Cardiology, RWTH Aachen University Hospital

Aachen, North Rhine-Westphalia, 52057, Germany

About this study

Patients with cardiac disorder have to undergo time- consuming and expensive examinations such as laboratory of cardiac biomarkers or ischemic diagnostic. To save time and money in this observational registry the probable distinction between cardiac and non- cardiac disorder in patients with vague thoracal disorder and the probability for coronary artery disease (determined via Grace Score) is examined via echographic myocardial strain analysis in 300 patients retrospectively to establish a cut off value corresponding to acute coronary disease also to prevent coronary angiography. Therefore patients undergo echography routinely with consecutive evaluation of systolic, diastolic and strain analysis to elevate exact statements with reference to deformation of the myocard and its velocity. Several study have shown that these strain parameters (circumferential and radial strain) enable vitality and ischemic diagnosis and therefore could be eligible for this purpose.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • thoracal cardiac or non cardiac disorder
  • signed informed consent

Exclusion criteria

  • glomerular filtration rate (GFR) < 60 ml/min
  • angina pectoris
  • acute myocardial infarction within 3 months prior inclusion
  • pregnancy

Treatment and study plan

retrospective echographic myocardial strain analysis refering to acute coronary syndrome

Other

retrospective evaluation for cut off value of circumferential and radial echographic strain parameters corresponding to acute coronary disease

Primary outcomes

  1. Determination of cut off value of circumferential and radial myocardial echographic strain data corresponding to acute coronary disease

    Time frame: 1 year

Sponsors and collaborators

Lead sponsor

RWTH Aachen University

Other

Registry information

Official study title

Analysis of Myocardial Deformation in Patients With Acute Coronary Disease

Acronym: ACS-Strain

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
Feb 6, 2015
Registry last updated
Feb 6, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.