Acute Cardiorespiratory Effects of E-cigarette Inhalation

It is estimated that 6 million people worldwide lose their lives due to tobacco use yearly. On average, cigarette smokers are estimated to die 10 years earlier than non-smokers. Ischemic heart disease, chronic obstructive pulmonary disease, stroke, respiratory illness, lung cancer and other cancers have all been linked to tobacco use. In recent years the electronic cigarette (e-cigarette) has been introduced to the market as an alternative to traditional cigarette smoking. E-cigarettes have been aggressively marketed as a cheaper, healthier, cleaner alternative to smoking in both advertising and media outlets, primarily targeting women and adolescents. With limited knowledge of e-cigarette vaping health effects in humans it has been challenging for governments and health officials to give advice and regulate the use of this novel product.

In the current study investigators aim to investigate acute cardiovascular and respiratory effects after active inhalation of e-cigarette in healthy human subjects.

Inclusion criteria

• Intermittent/sporadic cigarette smoking
• Normal clinical examination
• Normal EKG
• Normal blood tests
• Normal lung function

Exclusion criteria

• Cardiovascular disease
• Respiratory disease
• Systemic or chronic disorders or disease
• Symptoms of infection or inflammation within 2 weeks of the study
• BMI≥30
• Pregnancy
• Current habitual cigarette smokers