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Completed

NCT Number: NCT03160989

Acute and Chronic Responses to Blood Pressure After Exercise

The study will evaluate the variability of blood pressure in postmenopausal and hypertensive women after only one session and after training of ten weeks of combined physical exercises (aerobic and resisted).

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Key information

Age range

50 year–70 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

About this study

Before starting the training program, all the volunteers will sign the Free and Informed Consent Form (TCLE) and must present a medical certificate releasing the participation. In addition, the volunteers will respond to an anamnesis questionnaire and will undergo an anthropometric evaluation before the experimental sessions. The physical exercise program will be held three times a week for 10 weeks, containing aerobic exercise (exercise treadmill) and resistance exercises (bodybuilding). Initially, a familiarization of the ergometers used will be performed, followed by a session to evaluate the intensity of resistance exercise through a maximal repetition test (1RM), and a session to evaluate aerobic fitness through an incremental treadmill test.

Before starting the training, volunteers will perform a single exercise session, following the same exercise protocol. All the volunteers will be submitted to the evaluation of the blood pressure during 24 hours through the measurement of ambulatory blood pressure (ABPM) in three moments:

  • PR: pre-training rest - the volunteers will arrive at the laboratory, will be in rest for 15 minutes and after that they will place the ABPM, without having done any exercise.
  • PE: post exercise - upon arriving at the laboratory, the volunteers will be submitted to a single combined exercise session, will have a maximum interval of 20 minutes for the bath and will place the MAP device.
  • CR: rest after chronic training - after the end of the 10 weeks of training, the volunteers will be submitted to ABPM, again at rest, with a maximum interval of 72 hours, between the end of the training and the placement of the device.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Women aged between 50 and 70 years;
  • Be in the postmenopausal phase;
  • Be able to practice physical exercise on treadmill and resistance exercises (bodybuilding).
  • Present stage 1 hypertension, according to the guidelines of the Brazilian Society of Hypertension
  • Make use of anti-hypertensive medication, except beta-blockers
  • Participants should be evaluated with a cardiologist beforehand and present a certificate attesting that they are able to perform physical activities.
  • Do not present physical problems or cardiovascular complications that prevent the performance of physical exercises.

Exclusion criteria

  • Make use of beta-blockers
  • Present history of stroke or acute myocardial infarction;
  • Smoking;
  • Present diagnosis of Diabetes Mellitus.
  • Present renal pathologies
  • Use hormone replacement therapies

Treatment and study plan

Physical exercises

Other

The intervention will consist of a single session and after ten weeks of combined physical exercises (aerobic and resisted). All volunteers will participate in the same procedure.

Primary outcomes

  1. Change in ambulatory blood pressure variability in ten weeks

    Time frame: After ten weeks and before ten weeks of exercise training

    The ambulatory blood pressure measurement will be performed for 24 hours. With the information obtained in this measurement, blood pressure variability will be performed.

Secondary outcomes

  1. Comparison resting blood pressure

    Time frame: After ten weeks and before ten weeks of exercise training

    The resting blood pressure is performed after 15 minutes of sitting, measured three times and the mean is calculated for analysis

  2. Anthropometric assessments

    Time frame: After ten weeks and before ten weeks of exercise training

    Body composition of the volunteers

Sponsors and collaborators

Lead sponsor

Federal University of Uberlandia

Other

Registry information

Important dates

Study start
2016
Primary completion
2016
Study completion
2016
First posted
May 19, 2017
Registry last updated
May 22, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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